0000000000725542
AUTHOR
Ahmed Aboelmagd
Stereoselective Synthesis of New 4-Aryl-5-indolyl-1,2,4-triazole S- and N-β-Galactosides: Characterizations, X-ray Crystal Structure and Hirshfeld Surface Analysis
5-(1H-Indol-2-yl)-4-phenyl-2,4-dihydro-3H-1,2,4-triazole-3-thione 1a and 4-(4-chlorophenyl)-5-(1H-indol-2-yl)-2,4-dihydro-3H-1,2,4-triazole-3-thione 1b were galactosylated in the presence of NaHCO3 in ethanol to produce S-galactosides 3,4, whereas, in the presence of K2CO3 in acetone they produced a mixture of S- and N-galactosides 3-6 with a higher yield of S-galactosides over the respective N-galactosides. Improvement in the yields of N-galactosides was produced by thermal migration of the galactosyl moiety from sulfur to nitrogen using fusion. β-Stereoselectivity of galactosylation was determined using the coupling constant value 3J1,2, which exceeded 9.0 Hz in all prepared galactos…
CCDC 2243221: Experimental Crystal Structure Determination
Related Article: Mezna Saleh Altowyan, Matti Haukka, Saied M. Soliman, Assem Barakat, Ahmed T. A. Boraei, Ahmed Aboelmagd|2023|Crystals|13|797|doi:10.3390/cryst13050797
CCDC 2243222: Experimental Crystal Structure Determination
Related Article: Mezna Saleh Altowyan, Matti Haukka, Saied M. Soliman, Assem Barakat, Ahmed T. A. Boraei, Ahmed Aboelmagd|2023|Crystals|13|797|doi:10.3390/cryst13050797