0000000000733120

AUTHOR

A. Scherrer

showing 2 related works from this author

Risk for non-AIDS-defining and AIDS-defining cancer of early versus delayed initiation of antiretroviral therapy

2021

BACKGROUND: Immediate initiation of antiretroviral therapy (ART) regardless of CD4 cell count reduces risk for AIDS and non-AIDS-related events in asymptomatic, HIV-positive persons and is the standard of care. However, most HIV-positive persons initiate ART when their CD4 count decreases below 500 × 10 9 cells/L. Consequences of delayed ART on risk for non-AIDS-defining and AIDS-defining cancer, one of the most common reasons for death in HIV, are unclear. OBJECTIVE: To estimate the long-term risk difference for cancer with the immediate ART strategy.DESIGN: Multinational prospective cohort study.SETTING: The D:A:D (Data collection on Adverse events of anti-HIV Drugs) study, which included…

MaleHIV AIDSHIV Infections0302 clinical medicineInterquartile rangeRisk FactorsNeoplasmsMedicine030212 general & internal medicineProspective StudiesProspective cohort study0303 health sciencesIncidenceAbsolute risk reductionDrugsGeneral MedicineMiddle AgedViral LoadAntiretroviral therapy3. Good healthAIDSCancer treatmentPrevention policy and public healthCohortInfectious diseasesCohort studiesFemaleViral loadAdultmedicine.medical_specialtyAnti-HIV AgentsHIV Infections/drug therapySocio-culturaleTime-to-Treatment03 medical and health sciencesAcquired immunodeficiency syndrome (AIDS)SDG 3 - Good Health and Well-beingInternal medicineInternal MedicineHumansAdverse effect030306 microbiologybusiness.industryHIVCancermedicine.diseaseCD4 Lymphocyte CountCancer.Anti-HIV Agents/therapeutic use[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologiebusinessNeoplasms/epidemiologyAnnals of Internal Medicine
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Fission fragment anisotropy for the 242mAm fission isomer by spin exchange pumping with polarized rubidium vapour

1992

Abstract The foundations of an experiment have been worked out with which, in principle, the spin, hyperfine constants and the isomer shift of the 14 ms fission isomer 242mAm can be measured. Such an experiment would be based on the fission fragment anisotropy signal which has actually been observed in this work after spin exchange pumping with polarized rubidium vapour in an optical buffer gas cell. A decrease of the count rate of (12±4)% has been measured at 90% with respect to the quantization axis. From this result it is concluded that the nuclear spin of the 242mAm fission isomer must be larger than 1. The low-energy fission isomers originating from the 242Pu(d, 2n)242mAm reaction have…

Nuclear reactionNuclear and High Energy PhysicsCluster decayFissionChemistrychemistry.chemical_elementAmericiumRubidiumNuclear physicsPlutonium-242Physics::Atomic and Molecular ClustersAtomic physicsNuclear ExperimentSpin (physics)InstrumentationHyperfine structureNuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms
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