0000000000733403
AUTHOR
José Luis Díez Gil
Clinical and echocardiographic outcomes of transcatheter mitral valve repair in atrial functional mitral regurgitation.
Background: Isolated atrial fibrillation can cause mitral regurgitation (MR) in patients with normal left ventricular systolic function and no organic disease of the mitral valve. Little information is available regarding outcomes of Mitraclip in patients with atrial functional mitral regurgitation (AFMR). We aimed to evaluate 12-month clinical and echocardiographic outcomes of transcatheter mitral valve repair (TMVR) with MitraClip in patients with AFMR compared to those with ventricular functional or degenerative/mixed MR. Methods: Registry-based analysis of all consecutive patients who underwent TMVR and were included in the Spanish Registry of Mitraclip. Changes in MR and NYHA functiona…
Efecto de frecuencias cardiacas suprafisiológicas en el miocardio sometido a isquemias de distinta duración
La hipótesis de partida de la presente Tesis Doctoral fue: "El efecto que sobre la función del ventrículo izquierdo produce una frecuencia cardiaca suprafisiológica tras un episodio de isquemia miocárdica depende de la duración y/o repetición de dicha isquemia." Para comprobar la hipótesis de trabajo se marcaron los siguientes objetivos: 1) Objetivo principal: el estudio de las alteraciones de la función ventricular izquierda en un modelo animal de sobreestimulación ventricular precedida por diferentes protocolos de isquemia-reperfusión. 2) Objetivos secundarios: a) Comprobar si una sobreestimulación ventricular de dos horas de duración, a una frecuencia un 60% superior a la inicial, es cap…
Acute Kidney Injury After Percutaneous Edge-to-Edge Mitral Repair.
BACKGROUND In catheter-based procedures, acute kidney injury (AKI) is a frequent, serious complication ranging from 10% to 30%. In MitraClip (Abbott Vascular, Santa Clara, California), a usually contrast-free procedure, there is scarce data about its real incidence and impact. OBJECTIVES This study aimed to evaluate incidence, predictive factors, and midterm outcomes of AKI in patients with significant mitral regurgitation (MR) undergoing transcatheter valve repair with MitraClip. METHODS A total of 721 patients undergoing MitraClip were included. AKI was defined as an absolute or a relative increase in serum creatinine of >0.3 mg/dl or >= 50%, respectively, or the need for hemodialysis dur…