0000000000735444

AUTHOR

Tingting Chen

showing 3 related works from this author

WNK3 Maintains the GABAergic Inhibitory Tone, Synaptic Excitation and Neuronal Excitability via Regulation of KCC2 Cotransporter in Mature Neurons

2021

The activation of chloride (Cl-)permeable gamma (γ)-aminobutyric acid type A(GABAA) receptors induces synaptic inhibition in mature and excitation in immature neurons. This developmental "switch" in GABA function controlled by its polarity depends on the postnatal decrease in intraneuronal Cl- concentration mediated by KCC2, a member of cation-chloride cotransporters (CCCs). The serine-threonine kinase WNK3 (With No Lysine [K]), is a potent regulator of all CCCs and is expressed in neurons. Here, we characterized the functions of WNK3 and its role in GABAergic signaling in cultured embryonic day 18 (E18) hippocampal neurons. We observed a decrease in WNK3 expression as neurons mature. Knock…

Synaptic ExcitationGABAergic Inhibitory ToneGABAergic inhibitory toneNeurosciences. Biological psychiatry. NeuropsychiatryHippocampal formationInhibitory postsynaptic potentialsynaptic excitationCellular and Molecular NeuroscienceWNK3:Medicine [Science]Receptorneuronal excitabilityMolecular BiologyOriginal ResearchGene knockdownGABAA receptorChemistryCell biologyElectrophysiologynervous systemGABAergichyperpolarized EGABAKCC2 cotransporterMolecular NeuroscienceCotransporterRC321-571Frontiers in Molecular Neuroscience
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A High‐Capacity Negative Electrode for Asymmetric Supercapacitors Based on a PMo 12 Coordination Polymer with Novel Water‐Assisted Proton Channels

2020

The development of a negative electrode for supercapacitors is a critical challenge for the next-generation of energy-storage devices. Herein, two new electrodes formed by the coordination polymers [Ni(itmb)4 (HPMo12 O40 )]·2H2 O (1) and [Zn(itmb)3 (H2 O)(HPMo12 O40 )]·4H2 O (2) (itmb = 1-(imidazo-1-ly)-4-(1,2,4-triazol-1-ylmethyl)benzene), synthesized by a simple hydrothermal method, are described. Compounds 1 and 2 show high capacitances of 477.9 and 890.2 F g-1 , respectively. An asymmetric supercapacitor device assembled using 2 which has novel water-assisted proton channels as negative electrode and active carbon as positive electrode shows ultrahigh energy density and power density of…

chemistry.chemical_classificationSupercapacitorMaterials scienceProtonCoordination polymer02 engineering and technologyGeneral ChemistryPolymer010402 general chemistry021001 nanoscience & nanotechnology01 natural sciences0104 chemical sciencesBiomaterialschemistry.chemical_compoundChemical engineeringchemistryElectrodePolyoxometalateGeneral Materials Science0210 nano-technologyBiotechnologyPower densityDiodeSmall
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CCDC 1835308: Experimental Crystal Structure Determination

2020

Related Article: Guangning Wang, Tingting Chen, Carlos J. Gómez-García, Feng Zhang, Mingyi Zhang, Huiyuan Ma, Haijun Pang, Xinming Wang, and Lichao Tan|2020|Small|16|8|doi:10.1002/smll.202001626

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameterscatena-(hexacosakis(mu-oxo)-(mu-phosphato)-tetrakis(1-{[4-(1H-imidazol-1-yl)phenyl]methyl}-1H-124-triazole)-decaoxo-dodeca-molybdenum-nickel tetrahydrate)Experimental 3D Coordinates
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