0000000000737687

AUTHOR

Anselm Kampik

showing 2 related works from this author

Flicker Defined Form Perimetry in Glaucoma Suspects with Normal Achromatic Visual Fields

2014

To evaluate if repeated flicker-defined form (FDF) perimetry can detect visual field (VF) defects in glaucoma suspects with normal findings in achromatic standard automated perimetry (SAP).Patients with optic nerve heads (ONHs) or retinal nerve fiber layer (RNFL) findings clinically suspicious for glaucoma and normal SAP were enrolled. Patients underwent VF testing with FDF perimetry (Heidelberg Edge Perimetry, HEP) at two consecutive visits (HEP I and HEP II) and confocal scanning laser ophthalmoscopy with the Heidelberg Retina Tomograph (HRT). Abnormal HEP was defined by cluster-point analysis (CPA) and by the HEP specific glaucoma hemi-field test (GHT). Results were compared with an age-…

AdultMaleRetinal Ganglion Cellsmedicine.medical_specialtygenetic structuresOptic DiskVision DisordersVisual AcuityNerve fiber layerGlaucomalaw.inventionTonometry OcularCellular and Molecular Neurosciencechemistry.chemical_compoundNerve FiberslawOphthalmologymedicineHumansProspective StudiesIntraocular PressureHeidelberg retina tomographOptic Nerve Headsbusiness.industryGlaucomaRetinalMiddle Agedmedicine.diseaseeye diseasesSensory SystemsVisual fieldConfocal scanning laser ophthalmoscopyOphthalmologyEarly Diagnosismedicine.anatomical_structurechemistryAchromatic lensVisual Field TestsFemaleOcular Hypertensionsense organsVisual FieldsbusinessCurrent Eye Research
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Deep sequencing of the human retinae reveals the expression of odorant receptors

2017

Several studies have demonstrated that the expression of odorant receptors (ORs) occurs in various tissues. These findings have served as a basis for functional studies that demonstrate the potential of ORs as drug targets for a clinical application. To the best of our knowledge, this report describes the first evaluation of the mRNA expression of ORs and the localization of OR proteins in the human retina that set a stage for subsequent functional analyses. RNA-Sequencing datasets of three individual neural retinae were generated using Next-generation sequencing and were compared to previously published but reanalyzed datasets of the peripheral and the macular human retina and to reference…

retinagenetic structuresddc:570odorant receptorsnext-generation sequencingsense organstranscriptomeeye diseasesNeuroscienceOriginal Researchimmunohistochemistry (IHC)
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