0000000000739201

AUTHOR

James S. Wolffsohn

showing 13 related works from this author

Comparison of the influence of corneo-scleral and scleral lenses on ocular surface and tear film metrics in a presbyopic population

2018

PURPOSE: To assess and compare the effect of the corneo-scleral lenses (C-ScL) and scleral lenses (ScL) on tear film parameters and central corneal thickness (CCT) in healthy presbyopic subjects. METHODS: Thirty subjects wore two contact lenses (CLs), randomly assigned, of neutral power, but of different diameters, 12.7mm (C-ScL) and 18mm (ScL) and being equal in the others parameters: material (HS100) and centre thickness (0.29mm). At baseline, 20min after insertion and at 8h, the tear meniscus area (TMA) and CCT was measured (with optical coherence tomography) as well as tear osmolarity. RESULTS: TMA revealed statistical differences for both lenses at 20min (p<0.001), and also at 8h (p=0.…

Malemedicine.medical_specialtygenetic structuresPopulationNormal valuesCornea03 medical and health sciences0302 clinical medicineScleral lenshemic and lymphatic diseasesCorneaOphthalmologyHumansMedicineProspective Studieseducationeducation.field_of_studybusiness.industryOsmolar ConcentrationfungiBoth lensesEquipment DesignPresbyopiaGeneral MedicinePresbyopiaMiddle AgedContact Lenses Hydrophilicmedicine.diseaseeye diseasesOphthalmologymedicine.anatomical_structureTear meniscusTears030221 ophthalmology & optometryOptometryFemalesense organsbusinessOcular surfaceScleraTomography Optical Coherence030217 neurology & neurosurgeryFollow-Up StudiesOptometryContact Lens and Anterior Eye
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IMI Prevention of Myopia and Its Progression

2021

The prevalence of myopia has markedly increased in East and Southeast Asia, and pathologic consequences of myopia, including myopic maculopathy and high myopia-associated optic neuropathy, are now some of the most common causes of irreversible blindness. Hence, strategies are warranted to reduce the prevalence of myopia and the progression to high myopia because this is the main modifiable risk factor for pathologic myopia. On the basis of published population-based and interventional studies, an important strategy to reduce the development of myopia is encouraging schoolchildren to spend more time outdoors. As compared with other measures, spending more time outdoors is the safest strategy…

ulkoilugenetic structuresContact Lensesmedicine.medical_treatmenttaittovirheetehkäisyatropinePopulationVisual impairmentlikinäköisyysorthokeratologyGlobal HealthRefraction Ocularmyopia-associated optic neuropathyOptic neuropathy03 medical and health sciences0302 clinical medicineMyopiaPrevalencemedicineHumansRisk factorhigh myopiaeducationeducation.field_of_studySpecial Issuebusiness.industrypathologic myopiamyopic macular degenerationOrthokeratologyAccommodation Ocularpiilolasitmedicine.diseaseeye diseasesAmplitude of accommodationEyeglassesDisease Progression030221 ophthalmology & optometryOptometryMaculopathysense organsmedicine.symptombusinessAccommodation030217 neurology & neurosurgeryInvestigative Opthalmology &amp; Visual Science
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Chambered warm moist air eyelid warming devices – a review

2021

Background Eyelid warming is an important treatment for meibomian gland dysfunction (MGD). Specialized chambered devices, using warm moist air have been developed. Purpose To critically evaluate the literature on the safety and efficacy of chambered warm moist air devices in MGD treatment and pinpoint areas of future research. Methods PubMed and Embase were searched on 06 June 2021. The search term was ‘(warm OR heat OR steam OR goggle OR spectacle OR moist air) AND (meibomian OR MGD OR blepharitis OR eyelid OR dry eye OR DED)’. All relevant articles with available English full text were included. Results Eighteen articles assessing the application of chambered warm moist air eyelid warming…

medicine.medical_specialtyWarm moist airGeneral PracticeSigns and symptomsoppvarming av øyelokkreviewartikkeleyelid warming devicesDry eye diseasesPrimary outcomeVDP::Medisinske Fag: 700::Klinisk medisinske fag: 750::Oftalmologi: 754MedicineHumansBlepharitisBlephasteamwarm moist airBlephasteam; dry eye disease; eyelid warming devices; meibomian gland dysfunction; warm moist airEyelid warming devicesbusiness.industryMeibomian gland dysfunctionMeibomian GlandsøyelokkGeneral Medicinemeibomian gland dysfunctionmedicine.diseaseMeibomian gland dysfunctiondry eye diseaseeye diseasesSurgeryAllmänmedicinOphthalmologySteammedicine.anatomical_structureSymptom improvementTreatment studyTearsDry heatEyelid DiseasesDry Eye SyndromesEyelidsense organsbusiness:Medisinske Fag: 700::Klinisk medisinske fag: 750::Oftalmologi: 754 [VDP]
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Effect of contact lens surface properties on comfort, tear stability and ocular physiology.

2018

Aim: Retrospective analysis of different contact lens wearing groups suggests lens surface lubricity is the main factor influencing contact lens comfort. However, the examined commercially available contact lenses differ in material and design as well as surface properties. Hence this study isolates the contribution of lens surface properties using an ultra-thin coating technology. Methods: Nineteen habitual contact lens wearers (21.6. ±. 1.7years) wore formofilcon B soft monthly disposable contact lenses with and without coating technology modified surface properties for a month each in a randomised double-masked cross-over study. Objective non-invasive: breakup time (NIKBUT), NIKBUT avera…

0301 basic medicineMalemedicine.medical_specialtyVisual analogue scaleSurface Propertieslaw.invention03 medical and health sciencesOcular physiologyYoung Adult0302 clinical medicineOpticsDouble-Blind MethodlawOphthalmologySurveys and QuestionnairesRetrospective analysisMedicineHumansCoefficient of frictionDisposable EquipmentRetrospective StudiesCross-Over Studiesbusiness.industryGeneral MedicineContact Lenses Hydrophiliceye diseasesLens (optics)Contact lensOphthalmology030104 developmental biologyPatient SatisfactionTears030221 ophthalmology & optometryFemalebusinessGrading scaleOptometryContact lensanterior eye : the journal of the British Contact Lens Association
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Short-Term Impact of FS-LASIK and SMILE on Dry Eye Metrics and Corneal Nerve Morphology

2020

PURPOSE To analyze the short-term (up to 1 month) clinical outcomes in patients undergoing corneal laser refractive surgery and the impact on dry eye disease (DED) metrics and corneal nerves using in vivo confocal microscopy (IVCM). METHODS The unaided distance visual acuity, corrected distance visual acuity, and spherical equivalent refraction (SEQ) were determined in 16 and 13 patients undergoing FS-LASIK and SMILE, respectively. DED metrics assessed were Ocular Surface Disease Index, Dry Eye Questionnaire 5-items (DEQ-5), tear film osmolarity, tear meniscus height, noninvasive keratograph breakup time (NIKBUT), ocular staining, and meibomian gland atrophy. An automated analysis of cornea…

AdultMalemedicine.medical_specialtyTime FactorsVisual acuitygenetic structuresCorneal nervemedicine.medical_treatmentKeratomileusis Laser In SituVisual AcuityMeibomian glandKeratomileusisRefraction OcularCornea03 medical and health sciencesNerve Fibers0302 clinical medicineAtrophyRefractive surgeryOphthalmologymedicineHumansOcular Surface Disease IndexProspective StudiesMicroscopy Confocalbusiness.industryLASIKmedicine.diseaseeye diseasesOphthalmologymedicine.anatomical_structure030221 ophthalmology & optometryDry Eye SyndromesFemaleLasers Excimersense organsmedicine.symptombusiness030217 neurology & neurosurgeryFollow-Up StudiesCornea
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Update and guidance on management of myopia : European Society of Ophthalmology in cooperation with International Myopia Institute

2021

The prevalence of myopia is increasing extensively worldwide. The number of people with myopia in 2020 is predicted to be 2.6 billion globally, which is expected to rise up to 4.9 billion by 2050, unless preventive actions and interventions are taken. The number of individuals with high myopia is also increasing substantially and pathological myopia is predicted to become the most common cause of irreversible vision impairment and blindness worldwide and also in Europe. These prevalence estimates indicate the importance of reducing the burden of myopia by means of myopia control interventions to prevent myopia onset and to slow down myopia progression. Due to the urgency of the situation, t…

0301 basic medicinemedicine.medical_specialtygenetic structuresmedicine.medical_treatmentatropinePsychological interventionReviewsorthokeratologylikinäköisyyspreventive medicineehkäisevä lääketiede03 medical and health sciences0302 clinical medicineOphthalmologynäkövammatEpidemiologyMyopiaPrevalenceMedicineHumansmyopiaPreventive healthcareBlindnessbusiness.industrypathologic myopiaPathological myopiaOrthokeratologyHigh myopiaTreatment optionsGeneral Medicinemedicine.diseasetime spent outdoorsmyopia reduction interventionsMyopia Degenerative/epidemiologyeye diseasesOphthalmology030104 developmental biologyMyopia Degenerativesilmätaudit030221 ophthalmology & optometryDisease Progressionsense organsbusinessOrthokeratologic Proceduresblindnesssokeus
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Response of the aging eye to first day of modern material contact lens wear

2018

Objectives: To investigate the ocular surface of an aged population wearing a daily disposable contact lens over their first day of wear. Methods: Forty eyes from forty presbyopic subjects were fitted a daily CL (Delefilcon A). Tear osmolarity, tear meniscus area (TMA) and ocular surface aberrations (total higher order root means square (RMS)) were assessed at baseline (t0), at 20 minutes (t1) and after 8 hours (t2) of wear. Fluorescein corneal and conjunctival staining and tear break up time (TBUT) were performed at t0 and t2. Results: No statistically significant changes were found between t0, t1 and t2 for TMA, and between t0 and t2 for fluorescein corneal and conjunctival staining. TBUT…

AdultMaleUlls Acomodació i refracciómedicine.medical_specialtyAgingPopulationBaseline levelCornea03 medical and health scienceschemistry.chemical_compound0302 clinical medicineOphthalmologymedicineHumansProspective StudiesFluoresceineducationDisposable EquipmentVision OcularOsmoleeducation.field_of_studyOsmotic concentrationbusiness.industryOsmolar ConcentrationEquipment DesignPresbyopiaMiddle AgedContact Lenses HydrophilicTear osmolarityeye diseasesÒptica Aparells i instrumentsContact lensOphthalmologyTear meniscuschemistryPatient SatisfactionTears030221 ophthalmology & optometryDry Eye SyndromesFemalesense organsbusinessConjunctiva030217 neurology & neurosurgeryFollow-Up Studies
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Presbyopia and the aging eye: Existing refractive approaches and their potential impact on dry eye signs and symptoms.

2020

Every part of the human body is subject to aging, including the eye. Increased prevalence of dry eye disease with age is widely acknowledged: aging threatens ocular surface homeostasis, altering the normal functioning of the lacrimal functional unit and potentially leading to signs and symptoms of dry eye. Parallelly, two additional degenerative processes take place within the crystalline lens, leading to presbyopia and cataractogenesis. With continuously increasing life expectancies both conditions are expected to impact society further. Correction strategies for presbyopia and cataracts either directly or indirectly challenge ocular surface additionally. On one hand, contact lens presbyop…

Ulls Acomodació i refracciómedicine.medical_specialtyAginggenetic structuresmedicine.medical_treatmentSigns and symptomsRefraction Ocular03 medical and health sciences0302 clinical medicineCataractsOphthalmologyRefractive surgeryCorneamedicineHumansCorneal epitheliumAgedPotential impactbusiness.industryGeneral MedicinePresbyopiaPresbyopiamedicine.diseaseeye diseasesÒptica Aparells i instrumentsContact lensOphthalmologymedicine.anatomical_structureTears030221 ophthalmology & optometryDisease ProgressionDry Eye Syndromessense organsbusiness030217 neurology & neurosurgeryOptometryContact lensanterior eye : the journal of the British Contact Lens Association
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Opportunities and threats to contact lens practice: A global survey perspective

2021

Aim: To understand the views of contact lens (CL) practitioners across the globe regarding what they perceive as opportunities and threats in CL practice. Methods: A self-administered anonymised questionnaire, constructed in English and translated in six more languages, was distributed through reputed international professional bodies and academic institutions worldwide. The questionnaire included items on demographic characteristics, type of practice, and questions designed to explore practitioners’ perspective on the future of their CL practice over the next five years. Results: A total of 2408 valid responses were analysed. Multifocal CLs for presbyopia, CLs for myopia control, use of da…

Medical educationUniversitiesContact LensesPerspective (graphical)GlobeContact lens practicePresbyopiaGeneral MedicinePresbyopiamedicine.diseaseBiocompatible materialContact lensOphthalmologymedicine.anatomical_structureCLs upper limitsOpportunitieSurveys and QuestionnairesMyopiamedicineHumansDaily disposablePsychologyThreatOptometry
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Systemic, environmental and lifestyle risk factors for dry eye disease in a mediterranean caucasian population

2022

Abstract Objectives To assess systemic, environmental and lifestyle risk factors for dry eye disease (DED) in a Mediterranean Caucasian population. Methods A cross-sectional study was performed on 120 Caucasian participants aged between 18 and 89 years (47.0 ± 22.8 years). Medical history, information regarding environmental conditions and lifestyle, Ocular Surface Disease Index, Dry Eye Questionnaire-5, non-Invasive (Oculus Keratograph 5 M) breakup time, tear film osmolarity and ocular surface staining parameters were assessed in a single clinical session to allow DED diagnosis based on the guidelines of the Tear Film and Ocular Surface Society Dry Eye Workshop II Diagnostic Methodology Re…

Adultmedicine.medical_specialtyAdolescentDiseaseLogistic regressionYoung AdultRisk FactorsCaffeineInternal medicineEpidemiologyHumansMedicineOcular Surface Disease IndexMedical historyRisk factorLife StyleAgedAged 80 and overUnivariate analysisbusiness.industryGeneral MedicineMiddle Agedmedicine.diseaseMenopauseOphthalmologyCross-Sectional StudiesAnti-Anxiety AgentsTearsDry Eye SyndromesFemalebusinessOptometryContact Lens and Anterior Eye
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Hot towels

2023

Background Meibomian gland dysfunction (MGD) reduces quality-of-life and hinders work productivity of millions of patients, with high direct and indirect societal costs. Thickened meibum obstructs the glands and disrupts ocular surface health. Heating the eyelids to soften and express meibum from the glands can be beneficial. The most accessible method for eyelid warming uses heated, wet towels. However, the efficacy of this treatment is reliant on the methodology, and evidence-based best-practice recommendations are needed. Purpose To evaluate the literature on hot towels in MGD treatment and recommend a best-practice protocol for future research and patient treatment. Methods Studies were…

OphthalmologyEyelid warmingVDP::Medisinske Fag: 700::Klinisk medisinske fag: 750::Oftalmologi: 754:Medisinske Fag: 700 [VDP]Evaporative dry eyeHot towelsGeneral MedicineDry eye diseaseMeibomian gland dysfunctionOptometryContact Lens and Anterior Eye
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Objective analysis of contact lens fit.

2015

Purpose: To assess the validity and repeatability of objective compared to subjective contact lens fit analysis. Methods: Thirty-five subjects (aged 22.0. ±. 3.0 years) wore two different soft contact lens designs. Four lens fit variables: centration, horizontal lag, post-blink movement in up-gaze and push-up recovery speed were assessed subjectively (four observers) and objectively from slit-lamp biomicroscopy captured images and video. The analysis was repeated a week later. Results: The average of the four experienced observers was compared to objective measures, but centration, movement on blink, lag and push-up recovery speed all varied significantly between them (p 0.05). The 95% conf…

AdultMalegenetic structuresObjective analysisObjective assessmentCorneaDouble-Blind MethodStatisticsMyopiaHumansMathematicsFit/gap analysisBlinkingbusiness.industryObjective measurementReproducibility of ResultsGeneral MedicineRepeatabilityEquipment DesignContact Lenses HydrophilicCentrationConfidence intervalContact lensOphthalmologyFemaleNuclear medicinebusinessOptometryContact lensanterior eye : the journal of the British Contact Lens Association
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Systemic, environmental and lifestyle risk factors for dry eye disease in a mediterranean caucasian population

2021

Objectives: To assess systemic, environmental and lifestyle risk factors for dry eye disease (DED) in a Mediterranean Caucasian population. Methods: A cross-sectional study was performed on 120 Caucasian participants aged between 18 and 89 years (47.0 ± 22.8 years). Medical history, information regarding environmental conditions and lifestyle, Ocular Surface Disease Index, Dry Eye Questionnaire-5, non-Invasive (Oculus Keratograph 5 M) breakup time, tear film osmolarity and ocular surface staining parameters were assessed in a single clinical session to allow DED diagnosis based on the guidelines of the Tear Film and Ocular Surface Society Dry Eye Workshop II Diagnostic Methodology Report. A…

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