0000000000739428
AUTHOR
Anne Silvestre
Random anthelmintic treatments in sheep: targeted selective treatment for the dummies.
International audience
Mathematical models for the management of helminth parasites: from biological processes to the evolution of anthelmintic resistance
International audience; Helminth parasitic diseases are mainly controlled by anthelmintic treatments, but control schemes are now threatened by the large development of anthelmintic resistance. Integrated parasite management needs to be developed but processes underpinning parasite population dynamics and resistant gene evolution are still lacking. Here, we review the mathematical models that have been developed to understand the evolution of anthelmintic resistance in host-helminth parasite models (intestinal helminth parasites of herbivores and human soil-transmitted helminths). A first part is dedicated to generic models that allowed the understanding of processes underlying host-helmint…