0000000000745919

AUTHOR

Ana Gil-brusola

0000-0002-4418-3676

showing 3 related works from this author

Towards next-generation diagnostics for tuberculosis: identification of novel molecular targets by large-scale comparative genomics.

2020

5 páginas, 2 figuras. AVAILABILITY AND IMPLEMENTATION: The database of non-tuberculous mycobacteria assemblies can be accessed at: 10.5281/zenodo.3374377. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online: http://dx.doi.org/10.1093/bioinformatics/btz729

Statistics and ProbabilityTuberculosisGenomicsComputational biologyBiologyBiochemistryMycobacterium tuberculosis03 medical and health sciencesmedicineHumansTuberculosisDiscovery NotesMolecular Biology030304 developmental biologyComparative genomics0303 health sciences030306 microbiologyScale (chemistry)GenomicsMycobacterium tuberculosismedicine.diseasebiology.organism_classificationGenome Analysis3. Good healthComputer Science ApplicationsComputational MathematicsComputational Theory and MathematicsMycobacterium tuberculosis complexMolecular targetsIdentification (biology)BiomarkersBioinformatics (Oxford, England)
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Towards next generation diagnostics for tuberculosis: identification of novel molecular targets by large-scale comparative genomics

2019

AbstractTuberculosis remains one of the main causes of death worldwide. The long and cumbersome process of culturingMycobacterium tuberculosiscomplex (MTBC) bacteria has encouraged the development of specific molecular tools for detecting the pathogen. Most of these tools aim to become novel tuberculosis diagnostics, and big efforts and resources are invested in their development, looking for the endorsement of the main public health agencies. Surprisingly, no study had been conducted where the vast amount of genomic data available is used to identify the best MTBC diagnostic markers. In this work, we use large-scale comparative genomics to provide a catalog of 30 characterized loci that ar…

Comparative genomics0303 health sciencesTuberculosis030306 microbiologyGenomic dataDiagnostic markerComputational biologyBiologybiology.organism_classificationmedicine.disease3. Good health03 medical and health sciencesMycobacterium tuberculosis complexTuberculosis diagnosticsMolecular targetsmedicineIdentification (biology)030304 developmental biology
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Caracterización epidemiológica, clínica, microbiológica y genómica de Mycobacterium tuberculosis en el Departamento de Salud La Fe de Valencia

2017

Tesis doctoral, 152 págs

Departamento La Fe Valencia:CIENCIAS MÉDICAS ::Ciencias clínicas::Microbiología clínica [UNESCO]TuberculosisSecuenciación genómicaUNESCO::CIENCIAS MÉDICAS ::Ciencias clínicas::Microbiología clínica
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