0000000000746031

AUTHOR

Schiavone S.

showing 3 related works from this author

The multifaceted spectrum of liver cirrhosis in older hospitalised patients: Analysis of the REPOSI registry

2021

Abstract Background Knowledge on the main clinical and prognostic characteristics of older multimorbid subjects with liver cirrhosis (LC) admitted to acute medical wards is scarce. Objectives To estimate the prevalence of LC among older patients admitted to acute medical wards and to assess the main clinical characteristics of LC along with its association with major clinical outcomes and to explore the possibility that well-distinguished phenotypic profiles of LC have classificatory and prognostic properties. Methods A cohort of 6,193 older subjects hospitalised between 2010 and 2018 and included in the REPOSI registry was analysed. Results LC was diagnosed in 315 patients (5%). LC was ass…

Patient Discharge.RegistrieAgingmedicine.medical_specialtyCirrhosisphenotypeliver cirrhosisAftercareOlder populationNOolder people03 medical and health sciencesSocial support0302 clinical medicinePhenotypic analysisOlder patientsInternal medicinemedicineHumansRegistries030212 general & internal medicineLS4_4Hospital MortalityAgedbusiness.industryhospitalisationliver cirrhosiHazard ratioConfoundingphenotypesGeneral Medicinemedicine.diseasedisability; hospitalisation; liver cirrhosis; mortality; older people; phenotypes; Aged; Hospital Mortality; Hospitalization; Humans; Liver Cirrhosis; Registries; Aftercare; Patient DischargemortalityPatient DischargeHospitalizationdisabilityCohortdisability hospitalisation liver cirrhosis mortality older people phenotypes030211 gastroenterology & hepatologyGeriatrics and Gerontologybusinessdisability; hospitalisation; liver cirrhosis; mortality; older people; phenotypesHuman
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Underdiagnosis and undertreatment of osteoporotic patients admitted in internal medicine wards in Italy between 2010 and 2016 (the REPOSI Register)

2021

Purpose: To evaluate clinical features, treatments, and outcomes of osteoporotic patients admitted to internal medicine and geriatric wards compared with non-osteoporotic patients (REPOSI registry). Methods: We studied 4714 patients hospitalized between 2010 and 2016. We reported age, sex, educational level, living status, comorbidities and drugs taken, Cumulative Illness Rating Scale (CIRS), Barthel Index, Short-Blessed Test, 4-item Geriatric Depression Scale, serum hemoglobin, creatinine, and clinical outcomes. Osteoporosis was defined based on the diagnoses recorded at admission, according to the following ICD9: 733, 805-813, 820-823. Results: Twelve percent of the patients had a preadmi…

medicine.medical_specialtyEndocrinology Diabetes and Metabolismmedicine.medical_treatmentOsteoporosis030209 endocrinology & metabolismNO03 medical and health scienceschemistry.chemical_compound0302 clinical medicineEndocrinologyRating scaleInternal medicineDiabetes mellitusVitamin D and neurologyInternal MedicineMedicineeracturesHumansBisphosphonateMedical diagnosisbisphosphonates; eractures; osteoporosis; vitamin DVitamin DAgedCreatinineRehabilitationLS7_9Bisphosphonates; Fractures; Osteoporosis; Vitamin D.business.industryOsteoporosiBisphosphonatesmedicine.diseaseHospitalizationFracturechemistryItaly030220 oncology & carcinogenesisOsteoporosisGeriatric Depression ScaleVitamin D.businessBisphosphonates; Fractures; Osteoporosis; Vitamin D; Aged; Hospitalization; Humans; Internal Medicine; Italy; Vitamin D; OsteoporosisBisphosphonates; Fractures; Osteoporosis; Vitamin DFractures
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COVID-19 Vaccination in Pregnancy, Paediatrics, Immunocompromised Patients, and Persons with History of Allergy or Prior SARS-CoV-2 Infection: Overvi…

2021

To date, four vaccines have been authorised for emergency use and under conditional approval by the European Medicines Agency to prevent COVID-19: Comirnaty, COVID-19 Vaccine Janssen, Spikevax (previously COVID-19 Vaccine Moderna) and Vaxzevria (previously COVID-19 Vaccine AstraZeneca). Although the benefit–risk profile of these vaccines was proven to be largely favourable in the general population, evidence in special cohorts initially excluded from the pivotal trials, such as pregnant and breastfeeding women, children/adolescents, immunocompromised people and persons with a history of allergy or previous SARS-CoV-2 infection, is still limited. In this narrative review, we critically overv…

AllergyIMPACTCOVID-19 VaccineBreastfeedingReview ArticleToxicologySettore MED/42 - Igiene Generale E ApplicataCLINICAL CHARACTERISTICSPregnancyPharmacology (medical)Pregnancy Complications InfectiousChildOUTCOMESeducation.field_of_studyCANCERVaccinationEuropeCORONAVIRUS DISEASE 2019 CLINICAL CHARACTERISTICS CANCER RECIPIENTS SEVERITY OUTCOMES IMPACT RATESBreast FeedingChild PreschoolPractice Guidelines as TopicFemale2019-nCoV Vaccine mRNA-1273HumanAdultmedicine.medical_specialtyCOVID-19 Vaccines2019-nCoV Vaccine mRNA-1273; Adolescent; Adult; BNT162 Vaccine; Breast Feeding; COVID-19; COVID-19 Vaccines; ChAdOx1 nCoV-19; Child; Child Preschool; Europe; Female; Humans; Infant; Practice Guidelines as Topic; Pregnancy; Pregnancy Complications Infectious; SARS-CoV-2; Hypersensitivity; Immunocompromised HostAdolescentSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)PopulationMEDLINECORONAVIRUS DISEASE 2019Immunocompromised HostChAdOx1 nCoV-19medicineHypersensitivityHumansRATESeducationBNT162 VaccinePharmacologyPregnancybusiness.industrySARS-CoV-2COVID-19Infantmedicine.diseaseVaccine efficacyRECIPIENTSSEVERITYFamily medicinePregnancy Complications Infectioubusiness
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