The immunohistochemical peptidergic expression of leptin is associated with recurrence of malignancy in laryngeal squamous cell carcinoma.

Leptin is a peptide that plays a key role in the control of satiety, energy expenditure, food intake and various reproductive processes. In the last years, the expression of leptin had been found in malignant cells of various origins. The aim of this study is to evaluate leptin expression in human laryngeal squamous cell carcinoma (SCC) and to investigate its possible role in predicting prognosis. Leptin expression was determined by immunohistochemistry in pathological and healthy tissue specimens from 24 patients with laryngeal SCC. Specimens were stained with an anti-leptin antibody. All measurements were performed using a computer-based image analysis system and scale of staining intensi…

Riuso e rigenerazione del patrimonio edilizio e dello spazio pubblico delle aree interne nell’era post Covid-19

The contraction of relational public space in favor of private one was one of the consequences due to the Covid-19 containment, which generated deep changes on lifestyles. This situation leads not only to reformulate public policies on housing and services provision, but also to reconsider the territorial rebalancing between urban systems densely inhabited and internal areas of the country in demographic decline as a precondition of prevention contagion. Particularly, attention will be paid to a southern internal area where population density is low, high-unused housing stock is available and environmental standards are higher. The objective is to build a methodological proposal for support…

Centri minori delle aree interne: verso una riorganizzazione spaziale e funzionale post pandemia

Le misure relative al contenimento del Covid-19 hanno cambiato profondamente i nostri stili di vita nei mesi scorsi e ancora oggi, soprattutto per quanto concerne l’uso dello spazio pubblico. Improvvisamente lo spazio privato è diventato predominante a causa delle impellenti necessità dettate dal distanziamento sociale, talvolta con effetti drammatici. Tale situazione ha fatto emergere con tutta evidenza la necessità di ripensare le politiche pubbliche sulla questione abitativa e la dotazione dei servizi, suggerendo allo stesso tempo, come possibile strategia di prevenzione del contagio, il riequilibrio territoriale tra sistemi urbani densamente abitati e aree interne del Paese in declino d…

Utilità dell’ecografia intestinale nei pazienti con malattia celiaca a sierologia negativa