0000000000749157
AUTHOR
Nicole Picard-hagen
showing 5 related works from this author
Toxicologie comparative du fipronil et de son principal métabolite le fipronil sulfone: complémentarité des modèles animaux et cellulaires
2011
Un modèle de mesure de la clairance de la T4 à partir de culture d'hépatocytes a été développé afin de préciser le potentiel perturbateur thyroïdien relatif du fipronil et du fipronil sulfone par des approches de type data-réponse.
Regulatory and academic studies to derive reference values for human health: The case of bisphenol S
2022
We would like to thank the HBM4EU team including Petra Apel (UBA), Matthieu Meslin and Christophe Rousselle (Anses) for their scientific contribution, as well as the ANSES Working Group on endocrine disruption, and its scientific Anses coordinators François Pouzaud and Sandrine Charles.; International audience; The close structural analogy of bisphenol (BP) S with BPA, a recognized endocrine-disrupting chemical and a substance of very high concern in the European Union, highlights the need to assess the extent of similarities between the two compounds and carefully scrutinize BPS potential toxicity for human health. This analysis aimed to investigate human health toxicity data regarding BPS…
Anomalies de la fonction ovarienne et stratégies thérapeutiques hormonales chez la vache allaitante
2011
Functional abnormalities of the ovaries in lactating cows and the use of hormonal control of ovarian activity for therapeutic purposes are reviewed in this article. The purpose of zootechnical control cycles is discussed as well as the specific pathophysiological aspects in the lactating cow. Focus is given on anoestrus and ovary cysts.
Elaboration of a method to categorize substances of interest as regards to their potential endocrine disrupting activity: assessment and categorizati…
2021
EDCs are substances that alter function(s) of the endocrine system and consequently cause adverse health effects. The endocrine system consists of many cells and tissues that interact with each other and the rest of the body by means of hormones. This system is responsible for controlling a large number of processes in the body from gamete formation, to conception and early developmental processes such as organogenesis, and to most tissue and organ functions throughout life. EDCs interfere with endocrine function by many ways and, in doing so, lead to adverse effects on the health of humans and/or wildlife. Some of the observed health effects associated with EDCs include, butare not limited…
Elaboration of a list of substances of interest as regards to a potential endocrine activity and prioritisation strategy for assessment
2021
Endocrine Disruptor Chemicals (EDCs) are substances that alter function(s) of the endocrine system and consequently cause adverse health effects. The endocrine system consists of many cells and tissues that interact with each other and the rest of the body by means ofhormones. This system is responsible for controlling a large number of processes in the body from gamete formation, to conception and early developmental processes such as organogenesis, and to most tissue and organ functions throughout life. EDCs interfere withendocrine function by many ways and, in doing so, lead to adverse effects on the health of humans and/or wildlife. Some of the observed health effects associated with ED…