0000000000749704

AUTHOR

S. Schulz

Deep learning for diagnosis and survival prediction in soft tissue sarcoma.

Background Clinical management of soft tissue sarcoma (STS) is particularly challenging. Here, we used digital pathology and deep learning (DL) for diagnosis and prognosis prediction of STS. Patients and methods Our retrospective, multicenter study included a total of 506 histopathological slides from 291 patients with STS. The Cancer Genome Atlas cohort (240 patients) served as training and validation set. A second, multicenter cohort (51 patients) served as an additional test set. The use of the DL model (DLM) as a clinical decision support system was evaluated by nine pathologists with different levels of expertise. For prognosis prediction, 139 slides from 85 patients with leiomyosarcom…

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CCDC 171405: Experimental Crystal Structure Determination

Related Article: F.Thomas, S.Schulz, M.Nieger, K.Nattinen|2002|Chem.-Eur.J.|8|1915|doi:10.1002/1521-3765(20020415)8:8<1915::AID-CHEM1915>3.0.CO;2-Z

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CCDC 213920: Experimental Crystal Structure Determination

Related Article: F.Thomas, S.Schulz, H.Mansikkamaki, M.Nieger|2003|Angew.Chem.,Int.Ed.|42|5641|doi:10.1002/anie.200352332

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CCDC 213921: Experimental Crystal Structure Determination

Related Article: F.Thomas, S.Schulz, H.Mansikkamaki, M.Nieger|2003|Angew.Chem.,Int.Ed.|42|5641|doi:10.1002/anie.200352332

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CCDC 171411: Experimental Crystal Structure Determination

Related Article: F.Thomas, S.Schulz, M.Nieger, K.Nattinen|2002|Chem.-Eur.J.|8|1915|doi:10.1002/1521-3765(20020415)8:8<1915::AID-CHEM1915>3.0.CO;2-Z

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CCDC 213922: Experimental Crystal Structure Determination

Related Article: F.Thomas, S.Schulz, H.Mansikkamaki, M.Nieger|2003|Angew.Chem.,Int.Ed.|42|5641|doi:10.1002/anie.200352332

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CCDC 171410: Experimental Crystal Structure Determination

Related Article: F.Thomas, S.Schulz, M.Nieger, K.Nattinen|2002|Chem.-Eur.J.|8|1915|doi:10.1002/1521-3765(20020415)8:8<1915::AID-CHEM1915>3.0.CO;2-Z

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CCDC 171406: Experimental Crystal Structure Determination

Related Article: F.Thomas, S.Schulz, M.Nieger, K.Nattinen|2002|Chem.-Eur.J.|8|1915|doi:10.1002/1521-3765(20020415)8:8<1915::AID-CHEM1915>3.0.CO;2-Z

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CCDC 171404: Experimental Crystal Structure Determination

Related Article: F.Thomas, S.Schulz, M.Nieger, K.Nattinen|2002|Chem.-Eur.J.|8|1915|doi:10.1002/1521-3765(20020415)8:8<1915::AID-CHEM1915>3.0.CO;2-Z

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CCDC 171409: Experimental Crystal Structure Determination

Related Article: F.Thomas, S.Schulz, M.Nieger, K.Nattinen|2002|Chem.-Eur.J.|8|1915|doi:10.1002/1521-3765(20020415)8:83.0.CO;2-Z

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CCDC 171408: Experimental Crystal Structure Determination

Related Article: F.Thomas, S.Schulz, M.Nieger, K.Nattinen|2002|Chem.-Eur.J.|8|1915|doi:10.1002/1521-3765(20020415)8:8<1915::AID-CHEM1915>3.0.CO;2-Z

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CCDC 171407: Experimental Crystal Structure Determination

Related Article: F.Thomas, S.Schulz, M.Nieger, K.Nattinen|2002|Chem.-Eur.J.|8|1915|doi:10.1002/1521-3765(20020415)8:8<1915::AID-CHEM1915>3.0.CO;2-Z

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