0000000000751781

AUTHOR

Laura García-villodre

0000-0001-9094-7107

showing 2 related works from this author

Analysis of Brain Functions in Men with Prostate Cancer under Androgen Deprivation Therapy: A One-Year Longitudinal Study.

2021

The relationship between cognitive decline and androgen deprivation therapy (ADT) under luteinizing hormone-releasing hormone (LHRH) analogues is unclear, and there is a scarcity of longitudinal studies considering the interaction between cognition, depressive symptoms and sleep quality in men with prostate cancer (PCa) treated with ADT. This study aimed to determine if there were differences in the scores obtained in cognitive assessment, depressive symptoms, and sleep quality after one year of ADT and determine the interrelations between sleep, mood, and cognitive status. A prospective longitudinal observational study was designed, in which a cohort of men (mean age was 70.8 years) newly …

Longitudinal studymedicine.medical_specialty030232 urology & nephrologyGeneral Biochemistry Genetics and Molecular BiologyArticleAndrogen deprivation therapy03 medical and health sciences0302 clinical medicineInternal medicineneurotoxicityMedicineEffects of sleep deprivation on cognitive performanceCognitive declineAthens insomnia scalesleeplcsh:ScienceEcology Evolution Behavior and SystematicsDepression (differential diagnoses)cognitive functionbusiness.industryPaleontologyMoodSpace and Planetary Science030220 oncology & carcinogenesistestosteronedepressionandrogen-deprivation therapyGeriatric Depression Scalelcsh:QbusinessLife (Basel, Switzerland)
researchProduct

Frailty syndrome is associated with changes in peripheral inflammatory markers in prostate cancer patients undergoing androgen deprivation therapy.

2019

To evaluate the role of peripheral inflammation (leukocyte differential count, the proinflammatory cytokines IL-beta, TNF-α, IL-6, IL-8, and the inflammatory markers fibrinogen and C-reactive protein [CRP]) in frailty syndrome in patients with prostate cancer (CaP) undergoing antiandrogen therapy (ADT).A total of 46 men between 51 and 92 years of age with CaP and receiving ADT were classified as frail, prefrail or robust according to the Fried scale. A geriatric assessment was performed, based on the Minimental State Examination for cognitive function, the Barthel index for basic activities of daily living, the Yesavage scale for geriatric depression, and the Athens insomnia scale. In addit…

OncologyMalemedicine.medical_specialtyUrologyFrailty syndrome030232 urology & nephrologyInflammationFibrinogenSeverity of Illness IndexProinflammatory cytokineAndrogen deprivation therapy03 medical and health sciencesProstate cancer0302 clinical medicineInternal medicinemedicineHumansLymphocyte CountAthens insomnia scaleGeriatric AssessmentAgedAged 80 and overFrailtybusiness.industryProstatic NeoplasmsAndrogen AntagonistsMiddle Agedmedicine.diseaseCross-Sectional StudiesOncology030220 oncology & carcinogenesisBiomarker (medicine)medicine.symptomInflammation Mediatorsbusinessmedicine.drugUrologic oncology
researchProduct