0000000000756198

AUTHOR

E. Maran

showing 2 related works from this author

Effects of aldicarb and propoxur on cytotoxicity and lipid peroxidation in CHO-K1 cells

2010

Abstract Cytotoxic effects of aldicarb, its sulfone and sulfoxide, and propoxur, lipid peroxidation and antioxidant parameters in Chinese Hamster Ovary (CHO-K1) cells were determined. d , l -buthionine-( S , R )-sulfoximine (BSO) was assayed to determine the role of GSH in the protection against carbamate cytotoxicity. Pre-treatment with 60 μM BSO, induced a significant decrease in the glutathione reductase (GR; 64–141%), the glutathione peroxidase (GPx; 10–30%) and the glutathione S-transferase (GST; 59–93%) activities, and its GSH levels (79–85%), while the oxidized glutathione (GSSG) levels significantly increased (64–78%) respect to experiment non-BSO-pretreated. Carbamates BSO pre-trea…

InsecticidesAntioxidantmedicine.medical_treatmentGlutathione reductaseCHO CellsPharmacologyPropoxurToxicologymedicine.disease_causeAntioxidantsLipid peroxidationchemistry.chemical_compoundCricetulusCricetinaemedicineAnimalschemistry.chemical_classificationGlutathione peroxidaseGeneral MedicineGlutathionePropoxurMalondialdehydeGlutathionechemistryBiochemistryLipid PeroxidationAldicarbOxidative stressFood ScienceFood and Chemical Toxicology
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Effects of carbamates as oxidative stressors on glutathione levels and lipid peroxidation in CHO-K1 cells

2006

Lipid peroxidationchemistry.chemical_compoundBiochemistryChemistryGlutathione reductaseGeneral MedicineGlutathioneOxidative phosphorylationToxicologyGPX4Toxicology Letters
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