0000000000760778

AUTHOR

G. Jenster

showing 3 related works from this author

The Detection of Androgen Receptor Splice Variant 7 in Plasma-derived Exosomal RNA Strongly Predicts Resistance to Hormonal Therapy in Metastatic Pro…

2017

Abstract Background The androgen receptor splice variant 7 (AR-V7) is associated with resistance to hormonal therapy in castration-resistant prostate cancer (CRPC). Due to limitations of the methods available for AR-V7 analysis, the identification of a reliable detection method may facilitate the use of this biomarker in clinical practice. Objective To confirm AR-V7 as a predictor of resistance to hormonal therapy and develop a new approach to assess AR-V7 by highly sensitive digital droplet polymerase chain reaction (ddPCR) in plasma-derived exosomal RNA. Design, setting, and participants Plasma samples were collected from 36 CRPC patients before they began second-line hormonal treatment. …

Oncology0301 basic medicineMaleResistanceExosomeschemistry.chemical_compoundProstate cancer0302 clinical medicineProtein IsoformsNeoplasm MetastasisReceptorAged 80 and overProstate cancerMiddle AgedProstatic Neoplasms Castration-ResistantReceptors Androgen030220 oncology & carcinogenesisBenzamidesAdenocarcinomaBiomarker (medicine)Hormonal therapyAR-V7; Digital droplet PCR; Exosomes; Hormonal therapy; Pharmacogenetics; Prostate cancer; Resistance; UrologyAndrostenesHormonal therapymedicine.medical_specialtyAntineoplastic Agents Hormonalmedicine.drug_classUrologyCastration resistantAdenocarcinomaDisease-Free Survival03 medical and health sciencesSDG 3 - Good Health and Well-beingInternal medicineNitrilesPhenylthiohydantoinmedicineEnzalutamideHumansAgedDigital droplet PCRPlasma derivedbusiness.industryRNAAndrogen Receptor Splice Variant 7medicine.diseaseAndrogenEndocrinology030104 developmental biologychemistryPharmacogeneticsDrug Resistance NeoplasmCancer cellCancer researchRNAAR-V7businessPharmacogenetics
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Vesiclepedia:A Compendium for Extracellular Vesicles with Continuous Community Annotation

2012

Vesiclepedia is a community-annotated compendium of molecular data on extracellular vesicles.

human proteinpedia; exosomal proteins; delivery-system; breast-milk; url decay; cells; microvesicles; update; rna; biogenesisQH301-705.5Medical Biotechnology (with a focus on Cell Biology (including Stem Cell Biology) Molecular Biology Microbiology Biochemistry or Biopharmacy)610 Medicine & healthApoptosisComputational biology1100 General Agricultural and Biological SciencesBiologyVesiclepediaExosomesExosomeGeneral Biochemistry Genetics and Molecular Biology03 medical and health sciencesAnnotation0302 clinical medicineSDG 3 - Good Health and Well-being1300 General Biochemistry Genetics and Molecular Biology2400 General Immunology and MicrobiologyCommunity PageExoCartaBiology (General)Medicinsk bioteknologi (med inriktning mot cellbiologi (inklusive stamcellsbiologi) molekylärbiologi mikrobiologi biokemi eller biofarmaci)BiologyBiología y Biomedicina030304 developmental biologyUncategorized0303 health sciencesGeneral Immunology and MicrobiologyGeneral NeuroscienceMicrovesicleResearch2800 General NeuroscienceExtracellular vesicle11359 Institute for Regenerative Medicine (IREM)Extracellular vesiclesMicrovesiclesCompendiumCell biologyData sharingDatabases as Topic030220 oncology & carcinogenesisGeneral Agricultural and Biological SciencesExtracellular Space
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Fractionated Radiation of Primary Prostate Basal Cells Results in Downplay of Interferon Stem Cell and Cell Cycle Checkpoint Signatures

2018

Male0301 basic medicineTime FactorsCell cycle checkpointGenotypeUrologyCell Cycle Proteins03 medical and health sciencesBasal (phylogenetics)0302 clinical medicineText miningInterferonProstateBiomarkers TumorTumor Cells CulturedmedicineHumansFractionated radiationbusiness.industryProstatic NeoplasmsGene Expression Regulation NeoplasticPhenotype030104 developmental biologymedicine.anatomical_structure030220 oncology & carcinogenesisInterferon Regulatory FactorsNeoplastic Stem CellsCancer researchDose Fractionation RadiationStem cellTranscriptomebusinessmedicine.drugEuropean Urology
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