0000000000765315

AUTHOR

Ondrej Ludka

showing 6 related works from this author

Impact of temperature on obstructive sleep apnoea in three different climate zones of Europe: Data from the European Sleep Apnoea Database (ESADA)

2021

Recent studies indicate that ambient temperature may modulate obstructive sleep apnoea (OSA) severity. However, study results are contradictory warranting more investigation in this field. We analysed 19,293 patients of the European Sleep Apnoea Database (ESADA) cohort with restriction to the three predominant climate zones according to the Koppen-Geiger climate classification: Cfb (warm temperature, fully humid, warm summer), Csa (warm temperature, summer dry, hot summer), and Dfb (snow, fully humid, warm summer). Average outside temperature values were obtained and several hierarchical regression analyses were performed to investigate the impact of temperature on the apnea-hypopnea index …

Cognitive NeuroscienceSettore MED/10 - Malattie Dell'Apparato RespiratorioEnvironmentcomputer.software_genreBody Mass IndexCohort Studies03 medical and health sciencesBehavioral NeuroscienceSleep Apnea SyndromeSleep Apnea Syndromes0302 clinical medicineEnvironmental temperaturestomatognathic systemHumansMedicineOxygen saturation (medicine)Climate zonesSleep Apnea ObstructiveOxygen desaturationDatabasebusiness.industryTemperatureSleep Apnea Obstructive.General MedicineSleep in non-human animalsSleep-related breathing disordersnervous system diseasesrespiratory tract diseasesClinical neurologysleep&#8208030228 respiratory systemClimate zonerelated breathing disorderssleep-related breathing disorderHuman medicineCohort StudiebusinessBody mass indexcomputer030217 neurology & neurosurgeryHumanJournal of Sleep Research
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Blood pressure reduction following treatment with positive airway pressure in sleep apnea: data from the European Sleep Apnea Database

2020

Abstract Introduction Positive airway pressure (PAP) treatment modifies blood pressure (BP) in patients with obstructive sleep apnea (OSA). We aimed to explore which factors that influence the BP response to PAP therapy in the European Sleep Apnea Database (ESADA). Methods A total of 2662 OSA patients with PAP therapy ≥90 days were included in the analysis (74% male, age 55±11 years, body mass index 32.3±6.1 kg/m2, 47% hypertensives, apnea-hypopnea index 40±24 events/h, treatment duration 1.0±1.1 years, PAP compliance 5.2±1.9 h/day). Anthropometric data, co-medications and office BP were assessed at baseline and follow-up visit. Results Systolic and diastolic BP were modestly reduced after …

medicine.medical_specialtybusiness.industrymedicine.medical_treatmentSleep apneamedicine.diseaseObstructive sleep apneaBlood pressureSleep apnea syndromesWeight lossInternal medicinePositive airway pressuremedicineCardiologymedicine.symptomCardiology and Cardiovascular MedicinebusinessReduction (orthopedic surgery)European Heart Journal
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Positive airway pressure level based upper airway collapsibility classification - the European Sleep Apnea Database (ESADA)

2021

Background and objectives: Obstructive sleep apnea (OSA) patients with mild upper airway collapsibility represents a target group for potential non-positive airway pressure (PAP) treatment. We studied the clinical characteristics of this endotypic group in a large Pan-European sleep apnea registry. Methods: A retrospective analysis was performed in 2541 OSA patients with fixed PAP treatment (male 74%, age 53±11 years, body mass index [BMI] 33±6 kg/m2, apnea-hypopnea index [AHI] 41±25 events/h at baseline). Therapeutic PAP level ≤8 cm H2O was used as the cut-off to classify patients with mild upper airway collapsibility (Landry SA et al. Sleep 2017; 40:6). Results: Mean pressure of the PAP t…

medicine.medical_specialtybusiness.industryMean pressureSleep apneamedicine.diseaserespiratory tract diseasesObstructive sleep apneaNegatively associatedInternal medicineCohortPositive airway pressuremedicineCardiologyAirwaybusinessBody mass index
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Reference values for mean overnight saturation in sleep apnoea – the European Sleep Apnoea Database (ESADA)

2020

Introduction: Normative values for mean overnight oxygen saturation during sleep in apnoea patients stratified for age, BMI, and sleep apnoea severity are lacking. Aim: To establish reference intervals for overnight mean saturation in a large sleep apnoea patient cohort. Methods: Mean overnight oxygen saturation was analysed in adult patients (n=23,220) from the European Sleep Apnoea Database (ESADA, 30 sleep centres, 18 European countries). Data were classified according to age, gender, BMI ( Results: Mean overnight saturation was 93.0% (95% confidence interval (CI) 92.9 to 93.1%). Age influenced the adjusted mean nocturnal saturation (93.6%, 93.2%, 92.9%, 92.5%, 92.2% and 91.9% for those …

medicine.medical_specialtyDatabasebusiness.industryConfoundingcomputer.software_genreApnoea / HypopneaSleep medicineSleep in non-human animalsConfidence intervalReference valuesparasitic diseasesCohortmedicinebusinessSaturation (chemistry)computerOxygen saturation (medicine)Sleep and control of breathing
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Hyperlipidemia Prevalence and Cholesterol Control in OSA: Data from European Sleep Apnea Database (ESADA)

2019

European-Respiratory-Society (ERS) International Congress -- SEP 28-OCT 02, 2019 -- Madrid, SPAIN

medicine.medical_specialtyCholesterolbusiness.industryConfoundingnutritional and metabolic diseasesSleep apneaDiseasemedicine.diseasenervous system diseasesrespiratory tract diseasesObstructive sleep apneachemistry.chemical_compoundstomatognathic systemchemistryInternal medicineCohortHyperlipidemiamedicineIn patientbusinessHypoxia
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Cancer prevalence is increased in females with sleep apnoea: data from the ESADA study

2019

[No abstract available]

MaleobesityLetterDatabases FactualDownload[SDV]Life Sciences [q-bio]cigarette smokingPolysomnographycancer riskdisease burdenapnea hypopnea indexsleep disordered breathingstudy design0302 clinical medicinepolysomnographyRisk FactorsNothingcancer diagnosisNeoplasmsmiddle agedgenderPrevalence030212 general & internal medicineSleep studyobstructive sleep apneaSleep Apnea Obstructiveeducation.field_of_studyanthropometryquantitative analysismedicine.diagnostic_testadultrisk assessmentclinical trialcohort analysisprostate cancerpulse oximetry[SDV] Life Sciences [q-bio]Europenot availablecomorbidityagedfemalewaist hip ratiocolon cancerpriority journalrisk factorfactual databasedisease severitycerebrovascular accidentPulmonary and Respiratory Medicinemedicine.medical_specialtyalcohol consumptionintermittent hypoxiaPopulationMEDLINElymphomaSettore MED/10 - Malattie Dell'Apparato Respiratoriomalignant neoplasmcancer growth03 medical and health sciencesmelanomamedicinecancercross-sectional studyHumanscontrolled studyhumaneducationCancer prevalencehypoxiabusiness.industrystatistical modelConflict of interestpredictionmajor clinical studybody massoxygen saturationlung cancermulticenter studyCross-Sectional StudiesLogistic Modelsage030228 respiratory systemdisease severity assessmentFamily medicineoxygen desaturation indexhead and neck cancerHuman medicinebusinessneoplasmEuropean Respiratory Journal
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