0000000000765496

AUTHOR

Geert Poelmans

showing 1 related works from this author

Genome-wide association study of motor coordination problems in ADHD identifies genes for brain and muscle function.

2012

Item does not contain fulltext OBJECTIVES: Motor coordination problems are frequent in children with attention deficit/hyperactivity disorder (ADHD). We performed a genome-wide association study to identify genes contributing to motor coordination problems, hypothesizing that the presence of such problems in children with ADHD may identify a sample of reduced genetic heterogeneity. METHODS: Children with ADHD from the International Multicentre ADHD Genetic (IMAGE) study were evaluated with the Parental Account of Children's Symptoms. Genetic association testing was performed in PLINK on 890 probands with genome-wide genotyping data. Bioinformatics enrichment-analysis was performed on highly…

MaleProbandmedicine.medical_specialtyGENETICSAdolescentGenotypeDCN MP - Plasticity and memoryMedizinQUESTIONNAIRESocial SciencesCHILDRENGenome-wide association studySingle-nucleotide polymorphismDCN PAC - Perception action and controlBioinformaticsMental health [NCEBP 9]Polymorphism Single NucleotideGenomic disorders and inherited multi-system disorders DCN MP - Plasticity and memory [IGMD 3]03 medical and health sciences0302 clinical medicineSurveys and QuestionnairesADOLESCENTSmedicineHumansDCN PAC - Perception action and control NCEBP 9 - Mental healthddc:610Medizinische Fakultät » Universitätsklinikum Essen » LVR-Klinikum Essen » Klinik für Psychiatrie Psychosomatik und Psychotherapie des Kindes- und JugendaltersRestless legs syndromeAmyotrophic lateral sclerosisChildPsychiatryBiological Psychiatry030304 developmental biologyGenetic association0303 health sciencesGenetic heterogeneityGenomic disorders and inherited multi-system disorders [DCN PAC - Perception action and control IGMD 3]medicine.disease3. Good healthMotor coordinationMotor Skills DisordersPsychiatry and Mental healthAttention Deficit Disorder with HyperactivityChild PreschoolFemalePsychologyINTERVENTION030217 neurology & neurosurgeryGenome-Wide Association Study
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