0000000000766896
AUTHOR
Mohamed Abid
Rationale, design, and baseline characteristics in Evaluation of LIXisenatide in Acute Coronary Syndrome, a long-term cardiovascular end point trial of lixisenatide versus placebo
BACKGROUND: Cardiovascular (CV) disease is the leading cause of morbidity and mortality in patients with type 2 diabetes mellitus (T2DM). Furthermore, patients with T2DM and acute coronary syndrome (ACS) have a particularly high risk of CV events. The glucagon-like peptide 1 receptor agonist, lixisenatide, improves glycemia, but its effects on CV events have not been thoroughly evaluated.METHODS: ELIXA (www.clinicaltrials.gov no. NCT01147250) is a randomized, double-blind, placebo-controlled, parallel-group, multicenter study of lixisenatide in patients with T2DM and a recent ACS event. The primary aim is to evaluate the effects of lixisenatide on CV morbidity and mortality in a population …
Effect of the Converging Pipe on the Performance of a Lucid Spherical Rotor
Lucid spherical rotor is a cross-flow rotor developed to be installed within a pipeline. The purpose of installing this type of rotor is to collect excess energy available in gravity-fed water pipelines. In order to enhance the efficiency of the rotor which is installed in a channel, this paper aims to study the performance of Lucid spherical rotor with converging pipe. Numerical investigations were carried out to analyze the effect of the converging pipe on the performance of the rotor. Numerical simulations have been carried out using the unsteady Reynolds-averaged Navier–Stokes equations in conjunction with the realizable $$k-{\varepsilon }$$ turbulence model. The validation of the numer…