0000000000771406
AUTHOR
D. Monk
Recommendations for a nomenclature system for reporting methylation aberrations in imprinted domains
The analysis of DNA methylation has become routine in the pipeline for diagnosis of imprinting disorders, with many publications reporting aberrant methylation associated with imprinted differentially methylated regions (DMRs). However, comparisons between these studies are routinely hampered by the lack of consistency in reporting sites of methylation evaluated. To avoid confusion surrounding nomenclature, special care is needed to communicate results accurately, especially between scientists and other health care professionals. Within the European Network for Human Congenital Imprinting Disorders we have discussed these issues and designed a nomenclature for naming imprinted DMRs as well …
Hypomethylation of imprinted genes in term placenta samples conceived by IVF/ICSI is associated with concomitant changes in post-translational histones modifications
IF 4.990; International audience