0000000000771607
AUTHOR
Robert Blum
On the nature of a shell of young stars in the outskirts of the Small Magellanic Cloud
Understanding the evolutionary history of the Magellanic Clouds requires an in-depth exploration and characterization of the stellar content in their outer regions, which ultimately are key to tracing the epochs and nature of past interactions. We present new deep images of a shell-like over-density of stars in the outskirts of the Small Magellanic Cloud (SMC). The shell, also detected in photographic plates dating back to the fifties, is located at ~1.9 degr from the center of the SMC in the north-east direction.The structure and stellar content of this feature were studied with multi-band, optical data from the Survey of the MAgellanic Stellar History (SMASH) carried out with the Dark Ene…
GLRB allelic variation associated with agoraphobic cognitions, increased startle response and fear network activation: a potential neurogenetic pathway to panic disorder.
Contains fulltext : 177350.pdf (Publisher’s version ) (Closed access) The molecular genetics of panic disorder (PD) with and without agoraphobia (AG) are still largely unknown and progress is hampered by small sample sizes. We therefore performed a genome-wide association study with a dimensional, PD/AG-related anxiety phenotype based on the Agoraphobia Cognition Questionnaire (ACQ) in a sample of 1370 healthy German volunteers of the CRC TRR58 MEGA study wave 1. A genome-wide significant association was found between ACQ and single non-coding nucleotide variants of the GLRB gene (rs78726293, P=3.3 x 10-8; rs191260602, P=3.9 x 10-8). We followed up on this finding in a larger dimensional AC…