0000000000774784

AUTHOR

Claudio La Bua

showing 1 related works from this author

Deep learning network for exploiting positional information in nucleosome related sequences

2017

A nucleosome is a DNA-histone complex, wrapping about 150 pairs of double-stranded DNA. The role of nucleosomes is to pack the DNA into the nucleus of the Eukaryote cells to form the Chromatin. Nucleosome positioning genome wide play an important role in the regulation of cell type-specific gene activities. Several biological studies have shown sequence specificity of nucleosome presence, clearly underlined by the organization of precise nucleotides substrings. Taking into consideration such advances, the identification of nucleosomes on a genomic scale has been successfully performed by DNA sequence features representation and classical supervised classification methods such as Support Vec…

0301 basic medicineComputer scienceSpeech recognitionCell02 engineering and technologyComputational biologyGenomeDNA sequencing03 medical and health scienceschemistry.chemical_compoundDeep Learning0202 electrical engineering electronic engineering information engineeringmedicineNucleosomeNucleotideGeneSettore ING-INF/05 - Sistemi Di Elaborazione Delle Informazionichemistry.chemical_classificationSequenceSettore INF/01 - Informaticabiologybusiness.industryDeep learningnucleosomebiology.organism_classificationSubstringChromatinIdentification (information)030104 developmental biologymedicine.anatomical_structurechemistry020201 artificial intelligence & image processingEukaryoteNucleosome classification Epigenetic Deep learning networks Recurrent Neural NetworksArtificial intelligencebusinessDNA
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