0000000000776722

AUTHOR

Seyed Hossein Hosseini

showing 2 related works from this author

Antithrombotic Therapy in COVID-19: Systematic Summary of Ongoing or Completed Randomized Trials

2021

ABSTRACTEndothelial injury and microvascular/macrovascular thrombosis are common pathophysiologic features of coronavirus disease-2019 (COVID-19). However, the optimal thromboprophylactic regimens remain unknown across the spectrum of illness severity of COVID-19. A variety of antithrombotic agents, doses and durations of therapy are being assessed in ongoing randomized controlled trials (RCTs) that focus on outpatients, hospitalized patients in medical wards, and critically-ill patients with COVID-19. This manuscript provides a perspective of the ongoing or completed RCTs related to antithrombotic strategies used in COVID-19, the opportunities and challenges for the clinical trial enterpri…

medicine.medical_specialty2019-20 coronavirus outbreakCoronavirus disease 2019 (COVID-19)Hospitalized patientsbusiness.industrySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)law.inventionClinical trialRandomized controlled triallawAntithromboticmedicineIllness severityIntensive care medicinebusiness
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Recent Randomized Trials of Antithrombotic Therapy for Patients With COVID-19

2021

Endothelial injury and microvascular/macrovascular thrombosis are common pathophysiological features of coronavirus disease-2019 (COVID-19). However, the optimal thromboprophylactic regimens remain unknown across the spectrum of illness severity of COVID-19. A variety of antithrombotic agents, doses, and durations of therapy are being assessed in ongoing randomized controlled trials (RCTs) that focus on outpatients, hospitalized patients in medical wards, and patients critically ill with COVID-19. This paper provides a perspective of the ongoing or completed RCTs related to antithrombotic strategies used in COVID-19, the opportunities and challenges for the clinical trial enterprise, and ar…

medicine.medical_specialtyCoronavirus disease 2019 (COVID-19)business.industrymedicine.drug_classAnticoagulantState of the art review030204 cardiovascular system & hematologymedicine.diseaseThrombosislaw.inventionClinical trial03 medical and health sciences0302 clinical medicinePharmacotherapyRandomized controlled triallawAntithromboticMedicine030212 general & internal medicineCardiology and Cardiovascular MedicinebusinessIntensive care medicineJournal of the American College of Cardiology
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