0000000000788425

AUTHOR

M. Lagarde

showing 2 related works from this author

Human Immunodeficiency Virus Continuum of Care in 11 European Union Countries at the End of 2016 Overall and by Key Population: Have We Made Progress?

2020

Abstract Background High uptake of antiretroviral treatment (ART) is essential to reduce human immunodeficiency virus (HIV) transmission and related mortality; however, gaps in care exist. We aimed to construct the continuum of HIV care (CoC) in 2016 in 11 European Union (EU) countries, overall and by key population and sex. To estimate progress toward the Joint United Nations Programme on HIV/AIDS (UNAIDS) 90-90-90 target, we compared 2016 to 2013 estimates for the same countries, representing 73% of the population in the region. Methods A CoC with the following 4 stages was constructed: number of people living with HIV (PLHIV); proportion of PLHIV diagnosed; proportion of those diagnosed …

Male0301 basic medicinePsychological interventionHuman immunodeficiency virus (HIV)MedizinContinuum of care; Europe; HIV infection; Key population; Sex; Anti-Retroviral Agents; Continuity of Patient Care; European Union; HIV; Humans; Male; HIV InfectionsHIV InfectionsContinuum of care; Europe; HIV infection; Key population; Sexmedicine.disease_causekey population0302 clinical medicineContinuum of careHIV Infection030212 general & internal medicineMen having sex with menContinuum of caremedia_commoneducation.field_of_study[SDV.MHEP] Life Sciences [q-bio]/Human health and pathologyTransmission (medicine)Continuity of Patient CareEuropeInfectious DiseasesAcademicSubjects/MED00290Anti-Retroviral AgentsHIV infection continuum of care sex key population EuropeSexMicrobiology (medical)PopulationSocio-culturale03 medical and health sciencesAcquired immunodeficiency syndrome (AIDS)SDG 3 - Good Health and Well-beingmedicinemedia_common.cataloged_instanceHumansEuropean UnionEuropean unioneducationPandemicsHIV infection ; continuum of care ; sex ; key population ; Europebusiness.industrySARS-CoV-2COVID-19HIVmedicine.diseaseHIV infectioncontinuum of care030112 virologyMajor Articles and CommentariesKey populationAnti-Retroviral Agentbusiness[SDV.MHEP]Life Sciences [q-bio]/Human health and pathologyDemography
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Different metabolic behavior of long-chain n-3 polyunsaturated fatty acids in human platelets.

1988

Abstract Whereas numerous studies deal with the effects and metabolism of eicosapentaenoic acid (20:5( n −3)) in platelets, very few concern docosahexaenoic acid (22:6( n −3)), although both acids are consumed in equal amounts from most fish fat. The present paper reports the modulation of 22:6( n −3) oxygenation as well as that of endogenous arachidonic acid (20:4( n −6)) in 22:6( n −3)-rich platelets. Like the oxygenation of 20:5( n −3), the lipoxygenation of 22:6( n −3) occurred at a low level when incubated alone, but was markedly increased in the presence of 20:4( n −6), suggesting a similar peroxide tone dependency. 20:5( n −3) could not replace 20:4( n −6) in the increasing 22:6( n −…

chemistry.chemical_classificationBlood PlateletsbiologyDocosahexaenoic AcidsChemistryLipoxygenaseBiophysicsThromboxanesMetabolismArachidonic AcidsIn Vitro TechniquesBiochemistryEicosapentaenoic acidLipoxygenasechemistry.chemical_compoundEndocrinologyBiochemistryEicosapentaenoic AcidDocosahexaenoic acidbiology.proteinHumansPlateletArachidonic acidUnsaturated fatty acidPolyunsaturated fatty acidBiochimica et biophysica acta
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