0000000000798479

AUTHOR

Hana Lancova

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Anthropometric Variables as Mediators of the Association of Changes in Diet and Physical Activity With Inflammatory Profile

2020

AbstractBackgroundMechanisms underlying the associations of high levels of physical activity (PA) and adherence to the Mediterranean diet (MedDiet) with a better inflammatory profile remain unclear. Our objective was to assess the mediating role of changes in body mass index (BMI) and waist circumference (WC), as markers of body fat in the association of changes in PA and adherence to the MedDiet, with changes in the inflammatory profile.MethodThis study included 489 adults, aged 55–75 years, from the PREDIMED-Plus multicenter lifestyle intervention trial. An inflammatory score was calculated, based on 8 blood biomarkers: high-sensitivity C-reactive protein, interleukin 6, interleukin 8, in…

Agingmedicine.medical_specialtyWaistMediterranean diet030204 cardiovascular system & hematologyDiet Mediterraneanlaw.invention03 medical and health sciences0302 clinical medicineRandomized controlled triallawMediterranean dietInternal medicinemedicineHumans030212 general & internal medicineskin and connective tissue diseasesExerciseLife StyleBody mass indexInflammation2. Zero hungerbiologybusiness.industryLeptinC-reactive proteinAnthropometrybiology.proteinMediation analysisWaist circumferenceInterleukin 18sense organsGeriatrics and GerontologybusinessBody mass indexBiomarkersThe Journals of Gerontology: Series A
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