0000000000799711

AUTHOR

Jakub Kucharz

0000-0001-5388-8910

showing 3 related works from this author

Factors Affecting Sexual Function and Body Image of Early-Stage Breast Cancer Survivors in Poland: A Short-Term Observation

2019

Abstract Introduction Knowing the important factors influencing sexual function and body image might facilitate the recovery process of breast cancer survivors. Surgery type, relationship quality, and partner support might be modified to create a space for psychosexual intervention. Patients and Methods This retrospective questionnaire-based study was performed on 128 women aged 18 to 65 years who were free of disease at time of study entry and who underwent surgical treatment for breast cancer. Diagnostic and Statistical Manual of Mental Disorders criteria were used to assessed female sexual dysfunction (FSD). Changes in Sexual Functioning Questionnaire (CSFQ) were used to measure sexual f…

0301 basic medicineAdultCancer Researchmedicine.medical_specialtyAdolescentbody imagebreast cancer survivorsmedicine.medical_treatmentMammaplastySexual BehaviorFemale sexual dysfunctionBreast NeoplasmsMastectomy Segmental03 medical and health sciencesYoung Adultdeterminant factors0302 clinical medicineBreast cancersurgery timeQuality of lifeCancer SurvivorsInternal medicineMedicineHumansMastectomyAgedRetrospective Studiesbusiness.industryOdds ratioMiddle Agedmedicine.disease030104 developmental biologySexual dysfunctionOncologysexual dysfunction030220 oncology & carcinogenesisQuality of LifeAnxietyFemalePolandmedicine.symptombusinessSexual functionMastectomyClinical Breast Cancer
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Clinico-Pathological Features Influencing the Prognostic Role of Body Mass Index in Patients With Advanced Renal Cell Carcinoma Treated by Immuno-Onc…

2023

Background: Obesity has been associated with improved response to immunotherapy in cancer patients. We investigated the role of body mass index (BMI) in patients from the ARON-1 study (NCT05287464) treated by dual immuno-oncology agents (IO+IO) or a combination of immuno-oncology drug and a tyrosine kinase inhibitors (TKI) as first-line therapy for metastatic renal cell carcinoma (mRCC). Patients and methods: Medical records of patients with documented mRCC treated by immuno-oncology combinations were reviewed at 47 institutions from 16 countries. Patients were assessed for overall survival (OS), progression-free survival (OS), and overall clinical benefit (OCB), defined as the sum of the r…

Tumor ResponseOncologySurvivalUrologyImmunocomboNCT05287464ImmunotherapyObesitymRCC
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Global Real-World Outcomes of Patients Receiving Immuno-Oncology Combinations for Advanced Renal Cell Carcinoma: The ARON-1 Study

2023

Background: Immuno-oncology combinations have achieved survival benefits in patients with metastatic renal cell carcinoma (mRCC). Objective: The ARON-1 study (NCT05287464) was designed to globally collect real-world data on the use of immuno-combinations as first-line therapy for mRCC patients. Patients and methods: Patients aged ≥ 18 years with a cytologically and/or histologically confirmed diagnosis of mRCC treated with first-line immuno-combination therapies were retrospectively included from 47 International Institutions from 16 countries. Patients were assessed for overall survival (OS), progression-free survival (PFS), and overall clinical benefit (OCB). Results: A total of 729 patie…

Renal Cell CarcinomaImmunotherapyImmuno-oncology Combinations
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