0000000000802426

AUTHOR

M. Sambataro

Association of kidney disease measures with risk of renal function worsening in patients with type 1 diabetes

Background Albuminuria has been classically considered a marker of kidney damage progression in diabetic patients and it is routinely assessed to monitor kidney function. However, the role of a mild GFR reduction on the development of stage ≥3 CKD has been less explored in type 1 diabetes mellitus (T1DM) patients. Aim of the present study was to evaluate the prognostic role of kidney disease measures, namely albuminuria and reduced GFR, on the development of stage ≥3 CKD in a large cohort of patients affected by T1DM. Methods A total of 4284 patients affected by T1DM followed-up at 76 diabetes centers participating to the Italian Association of Clinical Diabetologists (Associazione Medici D…

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On the interdependence between ground and one-phonon RPA states

Working within a schematic model and in a boson formalism, we provide a descrip tion of the ground and first-excited states of a nuclear system in terms of two independent phonon operators. The description reveals itself quite effective in reproducing the energies of the states. A comparison between these two phonon operators allows us to localize a region where a correct description of these states is compatible with the Random Phase Approximation (RPA) requirement of a single phonon. This region is found to coincide approximately with that spanned by the standard RPA. Outside this region, the two phonons start differing rapidly therefore making the application of the RPA scheme impossible…

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