0000000000802464

AUTHOR

Alessandro Simonati

showing 2 related works from this author

Survey on treatments for primary headaches in 13 specialized juvenile Headache Centers: The first multicenter Italian study

2017

Abstract Aim The purpose of this retrospective multicenter study was to evaluate the use and the self-perceived efficacy and tolerability of pharmacological and non-pharmacological treatments in children and adolescents with primary headaches. Methods Study of a cohort of children and adolescents diagnosed with primary headache, consecutively referred to 13 juvenile Italian Headache Centers. An ad hoc questionnaire was used for clinical data collection. Results Among 706 patients with primary headaches included in the study, 637 cases with a single type of headache (migraine 76% – with and without aura in 10% and 67% respectively; tension-type headache 24%) were selected (mean age at clinic…

MalePediatricsmedicine.medical_specialtyAdolescentMigraine DisordersAdolescents; Children; Migraine; Primary headaches; Tension-type headache; Treatment; Pediatrics Perinatology and Child Health; Neurology (clinical)Tension-typeTriptansPizotifenPediatrics03 medical and health sciences0302 clinical medicinechildrenPrimary headacheBehavior TherapySurveys and QuestionnairesmedicineAcupunctureHumansAmitriptylinemigraine030212 general & internal medicineadolescentsPractice Patterns Physicians'ChildFlunarizineRetrospective Studiestreatmentbusiness.industryAnti-Inflammatory Agents Non-SteroidalGeneral Medicineadolescents; children; migraine; primary headaches; tension-type headache; treatmentPerinatology and Child Healthmedicine.diseasetension-type headacheMigraineTolerabilityItalyPediatrics Perinatology and Child HealthCohortAnticonvulsantsFemaleprimary headachesNeurology (clinical)businessheadache030217 neurology & neurosurgeryPrimary headaches; Migraine; Tension-type; headache; Treatment; Children; Adolescentsmedicine.drug
researchProduct

Human pathology in NCL

2013

AbstractIn childhood the neuronal ceroid lipofuscinoses (NCL) are the most frequent lysosomal diseases and the most frequent neurodegenerative diseases but, in adulthood, they represent a small fraction among the neurodegenerative diseases. Their morphology is marked by: (i) loss of neurons, foremost in the cerebral and cerebellar cortices resulting in cerebral and cerebellar atrophy; (ii) an almost ubiquitous accumulation of lipopigments in nerve cells, but also in extracerebral tissues. Loss of cortical neurons is selective, indiscriminate depletion in early childhood forms occurring only at an advanced stage, whereas loss of neurons in subcortical grey-matter regions has not been quantit…

AdultElectron microscopy; Brain; Extracerebral tissues; Granular osmiophilic deposits; Curvilinear; FingerprintPathologymedicine.medical_specialtyBatten diseaseFingerprintContext (language use)Extracerebral tissuesProgressive myoclonus epilepsyBiologyNeuronal Ceroid-LipofuscinosesCurvilinearElectron microscopymedicineHumansMolecular BiologyTripeptidyl-Peptidase 1BrainPPT1Anatomymedicine.diseaseCLN3DNAJC5Molecular MedicineGranular osmiophilic depositsNeuronal ceroid lipofuscinosisCerebellar atrophyBiochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
researchProduct