0000000000810461
AUTHOR
V. Cataldo
Hölder Continuity up to the Boundary of Minimizers for Some Integral Functionals with Degenerate Integrands
We study qualitative properties of minimizers for a class of integral functionals, defined in a weighted space. In particular we obtain Hölder regularity up to the boundary for the minimizers of an integral functional of high order by using an interior local regularity result and a modified Moser method with special test function.
Reduction of plasma granzyme A correlates with severity of sepsis in burn patients.
The risk of mortality is high in burn patients and correlates with age, burn area extent, and sepsis. Immunosuppression has been reported to occur after severe burn. Cytotoxic cells possess specialized granules containing perforin and a group of serine proteases (granzymes). Granzyme A is a serine protease constitutively expressed by gammadelta and NK cells, in agreement with their functional cytolytic potential. In vitro studies have shown that GrA may be released extracellularly during cytotoxic cell degranulation, indicating the activation of cytotoxic cells. The aim of our study was to determine plasma GrA activity in burned patients and to verify if decreased GrA levels were associated…