0000000000815822

AUTHOR

Mohamed L. Ashour

0000-0002-9270-6267

showing 2 related works from this author

Xanthones and sesquiterpene derivatives from a marine-derived fungus Scopulariopsis sp.

2016

Abstract Two new xanthone derivatives, 12-dimethoxypinselin ( 1 ) and 12- O -acetyl-AGI-B4 ( 2 ), as well as two new phenolic bisabolane-type sesquiterpenes, 11,12-dihydroxysydonic acid ( 15 ) and 1-hydroxyboivinianic acid ( 16 ), together with one new alkaloid, scopulamide ( 21 ) and one new α-pyrone derivative, scopupyrone ( 26 ), in addition to twenty-three known compounds ( 3 – 14 , 17 – 20 , 22 – 25 , 27 – 29 ) were isolated from solid rice cultures of the marine-derived fungus Scopulariopsis sp. obtained from the Red Sea hard coral Stylophora sp. All compounds were unambiguously identified through extensive NMR spectroscopic analyses, and by comparison with the literature. Marfey's re…

biology010405 organic chemistryChemistryStereochemistryMouse LymphomaAlkaloidOrganic ChemistryAbsolute configurationFungusbiology.organism_classificationSesquiterpene01 natural sciencesBiochemistry0104 chemical sciencesXanthone Derivatives010404 medicinal & biomolecular chemistrychemistry.chemical_compoundTermészettudományokDrug DiscoveryXanthoneScopulariopsisKémiai tudományokTetrahedron
researchProduct

Diversity of Pharmacological Properties in Chinese and European Medicinal Plants: Cytotoxicity, Antiviral and Antitrypanosomal Screening of 82 Herbal…

2011

In an extensive screening, the antiviral, antitrypanosomal and anticancer properties of extracts from 82 plants used in traditional Chinese medicine and European phytomedicine were determined. Several promising plants that were highly effective against hepatitis B virus (HBV), bovine viral diarrhoea virus (BVDV)—a flavivirus used here as a surrogate in vitro model of hepatitis C virus, trypanosomes (Trypanosoma brucei brucei) and several cancer cell lines were identified. Six aqueous extracts from Celosia cristata, Ophioglossum vulgatum, Houttuynia cordata, Selaginella tamariscina, Alpinia galanga and Alpinia oxyphylla showed significant antiviral effects against BVDV without toxic effects …

food.ingredientAlpinia galangagastrointestinal tumorsTrypanosoma brucei bruceiSelaginella tamariscinaPharmacologyHedyotis diffusaPhytomedicinetraditional Chinese medicinefoodHepG2 2.2.15Panax notoginsenglcsh:QH301-705.5BVDVNature and Landscape ConservationKadsura longipedunculataEcologybiologyEcological ModelingCoptis chinensisbiology.organism_classificationAgricultural and Biological Sciences (miscellaneous)Houttuynia cordataanticancer drugs; gastrointestinal tumors; traditional Chinese medicine; cytotoxicity; hepatitis B; hepatitis C; HepG2 2.2.15; BVDV; <em>Trypanosoma brucei brucei</em>anticancer drugslcsh:Biology (General)cytotoxicityhepatitis Bhepatitis CDiversity
researchProduct