0000000000844656

AUTHOR

Philippe Nguyen

showing 2 related works from this author

Proceedings of Réanimation 2017, the French Intensive Care Society International Congress

2017

biologybusiness.industry030208 emergency & critical care medicineLymphocyte proliferationCritical Care and Intensive Care MedicineMeeting Abstractslaw.invention03 medical and health sciencesInterleukin 100302 clinical medicine030228 respiratory systemlawPD-L1ImmunologyPostoperative infectionCardiopulmonary bypassbiology.proteinMedicine030212 general & internal medicinebusinessAnnals of Intensive Care
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Diagnosis of Heparin-Induced Thrombocytopenia: Development and Validation of a Predictive Clinical Score Based on Objective Features Identified by a …

2019

Background: Diagnosis of heparin-induced thrombocytopenia (HIT) is based on a composite of clinical likelihood and laboratory testing. We aimed to develop a diagnostic score derived from multivariate analysis of clinical features, including platelet count changes, prospectively recorded in patients with suspected HIT. Methods: This multinational observational study (ClinicalTrials.gov no. NCT00748839) included 2280 adult patients with suspected HIT: 1597 (derivation cohort) formed the basis for developing the scoring system, subsequently validated in 683 additional randomly selected patients (validation cohort). HIT was diagnosed by two independent adjudicators based on clinical features, l…

medicine.medical_specialtyMultivariate analysisbusiness.industryMajor traumamedicine.diseaseIntensive care unitlaw.inventionInformed consentlawInternal medicineHeparin-induced thrombocytopeniaGood clinical practiceMedicineObservational studybusinessProspective cohort studySSRN Electronic Journal
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