0000000000844902

AUTHOR

Jean-christophe Richard

showing 2 related works from this author

Proceedings of Réanimation 2017, the French Intensive Care Society International Congress

2017

biologybusiness.industry030208 emergency & critical care medicineLymphocyte proliferationCritical Care and Intensive Care MedicineMeeting Abstractslaw.invention03 medical and health sciencesInterleukin 100302 clinical medicine030228 respiratory systemlawPD-L1ImmunologyPostoperative infectionCardiopulmonary bypassbiology.proteinMedicine030212 general & internal medicinebusinessAnnals of Intensive Care
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Remdesivir for the Treatment of Hospitalised Patients with COVID-19 (DisCoVeRy): A Randomised, Controlled, Open-Label Trial

2021

Background: The antiviral efficacy of remdesivir is still controversial. We aimed at evaluating its clinical effectiveness in patients with COVID-19 requiring oxygen and/or ventilator support. Methods: In this European multicentre, open-label, parallel-group, randomised, controlled trial in adults hospitalised with COVID-19 (DisCoVeRy, NCT04315948; EudraCT2020-000936-23), participants were randomly allocated to receive usual standard of care alone or in combination with intravenous remdesivir (200 mg on day 1, then 100 mg once-daily for 9 days or until discharge). Treatment assignation was performed via web-based randomisation stratified on illness severity and administrative European regio…

education.field_of_studymedicine.medical_specialtybusiness.industryPopulationDeclarationCommissionTreatment and control groupsInformed consentFamily medicineHealth caremedicinemedia_common.cataloged_instanceEuropean unioneducationbusinessPsychology[SDV.MHEP]Life Sciences [q-bio]/Human health and pathologyDeclaration of Helsinkimedia_commonSSRN Electronic Journal
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