0000000000848401
AUTHOR
A. Calvo
The erosional response of Calcareous soils along a climatological gradient in Southeast Spain
Abstract The erosional response of calcareous soils along a climatological gradient in Alicante, SE Spain was studied. The erosional response was defined in terms of indicators obtained from field rainfall simulation experiments and laboratory studies of soil aggregation. Measurements were made at seven sites on limestones and marls between Benidorm with an annual average rainfall of 400 mm yr −1 and Coll de Rates (annual rainfall 900 mm yr −1 ). The sites were on matorral vegetation affected to varying intensities by grazing and fire. At the seven locations, soil aggregation was studied by sieving, by the single water drop test and by a Microscan particle-sizer. Rainfall simulation experim…
Conventional radiofrequency treatment in five patients with trigeminal neuralgia
Introduction: In trigeminal neuralgia, when drug treatment proves ineffective, other management options must be considered. In this context, conventional radiofrequency of Gasser’s ganglion is a safe and effective alternative. Material and Methods: We describe 5 patients with long-evolving trigeminal neuralgia subjected to conventional radiofrequency according to the Sweet technique, with a follow-up of two years. Results: Pain relief was complete after two months in all cases. One patient suffered an unexpected episode of nausea, vomiting and foul odor sensation that subsided after three days of rest and drug treatment. Three patients described non-painful hypoesthesia in the region of the…
Design and operation of a small and portable rainfall simulator for rugged terrain
A rainfall simulator designed to perform experiments in rugged terrain is presented. The portability of the apparatus allows the researcher to work in remote areas and on steep slopes. Rainfall intensity and distribution within the plot (0.24 m2) and drop-size were measured under different water pressure. For the best simulated rainfall distribution (1.55 kg cm2 of water pressure and 55 mm h−1 of rain intensity) the drop velocity and the kinetic energy were measured.
Effect of RNS60 in amyotrophic lateral sclerosis: a phase II multicentre, randomized, double-blind, placebo-controlled trial
Background and purpose: Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with limited treatment options. RNS60 is an immunomodulatory and neuroprotective investigational product that has shown efficacy in animal models of ALS and other neurodegenerative diseases. Its administration has been safe and well tolerated in ALS subjects in previous early phase trials. Methods: This was a phase II, multicentre, randomized, double-blind, placebo-controlled, parallel-group trial. Participants diagnosed with definite, probable or probable laboratory-supported ALS were assigned to receive RNS60 or placebo administered for 24 weeks intravenously (375 ml) once a week and via nebul…
The Impact of Climatic Change and Land Use on the Hydrological Response of Mediterranean Soils; a Study along a Climatological Gradient in Crete (Greece)
Abstract To help understand the impact of Climatic Change on the soils of the Mediterranean area, measurements of physical soil properties were carried out in a mountain zone in Crete (Greece), following a climatological gradient. Four experimental slopes were chosen, south facing and situated on limestone lithology. Soil hydrological properties including infiltration, runoff and sediment concentration, were measured and the percentage of waterstable microaggregation in the soil was calculated and used as an indicator of soil degradation. It was found that as well as climate, soil properties were highly affected by the extensive land use of the area, intensive grazing by goats and small sca…
Properties and erosional response of soils in a degraded ecosystem in Crete (Greece)
To study desertification processes relating to soil erosion, a climatological and altitudinal gradient from south to north was selected in Crete (Greece) and four locations were selected along the gradient. At the locations precipitation ranged from 1400 mm/year at the highest location to 400 mm/year at the lowest. All locations are affected by the actual land use: intensive grazing, small controlled fires, and abandoned agricultural terraces. Representative soil profiles were described in the field and analyzed in the laboratory, and rainfall simulation experiments in the field measured soil erosion over different soil surfaces and land uses. Data on physical and chemical properties were o…
Seed population dynamics on badland slopes in southeastern Spain
6 páginas, figuras, tablas.
Vulnerability of Mediterranean ecosystems to Climatic Change, study of soil degradation under different climatological conditions in an altitudinal transect in the south east of Spain
Abstract To investigate the potential response of soils to climatic change, measurements of soil physical and chemical properties were carried out during a year in a mountain zone in Alicante (Spain), along an altitudinal and climatological gradient. Hydrological properties (infiltration runoff and sediment concentration) were measured under winter and summer conditions. Chemical and physical soil properties were analyzed for reference soil profiles along the transect. The erosional response of the soils as well as soil properties like organic matter and CEC are found to be under the direct influence of the climate, and as a result they have to be considered as important factors in the dese…
Genetic counselling in ALS: facts, uncertainties and clinical suggestions
The clinical approach to patients with amyotrophic lateral sclerosis (ALS) has been largely modified by the identification of novel genes, the detection of gene mutations in apparently sporadic patients, and the discovery of the strict genetic and clinical relation between ALS and frontotemporal dementia (FTD). As a consequence, clinicians are increasingly facing the dilemma on how to handle genetic counselling and testing both for ALS patients and their relatives. On the basis of existing literature on genetics of ALS and of other late-onset life-threatening disorders, we propose clinical suggestions to enable neurologists to provide optimal clinical and genetic counselling to patients and…
Radiofrequency treatment of cervicogenic headache
Objectives: In the clinical management of facial pain, a possible cervical origin must be considered. A clinical exploration is therefore essential. The disorder originates in the intimate connections between the cranial portion of the spinal cord and the trigeminal system. Although solid evidence supporting the use of radiofrequency (RF) treatment is lacking, it remains one of the management options to be taken into account. The present study evalu - ates the efficacy of RF in application to cervicogenic headache. Study design: We present three cases of severe facial pain arising from different cervical structures. Results: In two cases the pain originated in cervical roots C2 and C3, whil…
Mutations in the Matrin 3 gene cause familial amyotrophic lateral sclerosis.
MATR3 is an RNA- and DNA-binding protein that interacts with TDP-43, a disease protein linked to amyotrophic lateral sclerosis (ALS) and frontotemporal dementia. Using exome sequencing, we identified mutations in MATR3 in ALS kindreds. We also observed MATR3 pathology in ALS-affected spinal cords with and without MATR3 mutations. Our data provide more evidence supporting the role of aberrant RNA processing in motor neuron degeneration. © 2014 Nature America, Inc. All rights reserved.