0000000000855732

AUTHOR

Vitalija Petrenkiene

showing 1 related works from this author

Gene polymorphisms of micrornas in Helicobacter pylori-induced high risk atrophic gastritis and gastric cancer.

2013

Background and aims MicroRNAs (miRNAs) are known for their function as translational regulators of tumor suppressor or oncogenes. Single nucleotide polymorphisms (SNPs) in miRNAs related genes have been shown to affect the regulatory capacity of miRNAs and were linked with gastric cancer (GC) and premalignant gastric conditions. The purpose of this study was to evaluate potential associations between miRNA-related gene polymorphisms (miR-27a, miR-146a, miR-196a-2, miR-492 and miR-608) and the presence of GC or high risk atrophic gastritis (HRAG) in European population. Methods Gene polymorphisms were analyzed in 995 subjects (controls: n = 351; GC: n = 363; HRAG: n = 281) of European descen…

Bacterial DiseasesAtrophic gastritislcsh:MedicineGastroenterologyRNA interferenceGastrointestinal CancersBasic Cancer ResearchGenotypeOdds Ratiolcsh:ScienceStomach and DuodenumGeneticsMultidisciplinarybiologyInfectious DiseasesOncologyGastritisMedicineGastritismedicine.symptomResearch ArticleGastritis Atrophicmedicine.medical_specialtySingle-nucleotide polymorphismGastroenterology and HepatologyPolymorphism Single NucleotideWhite PeopleStomach NeoplasmsInternal medicineGastrointestinal TumorsGeneticsmedicineHumansAlleleBiologyHelicobacter pylorilcsh:RCancers and NeoplasmsCancerOdds ratioHelicobacter pylorimedicine.diseasebiology.organism_classificationMicroRNAsGastric CancerLogistic ModelsGenetic Polymorphismlcsh:QGene expressionPopulation GeneticsPLoS ONE
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