0000000000856716

AUTHOR

Adrià Punset

showing 2 related works from this author

The DrosDel Deletion Collection: A Drosophila Genomewide Chromosomal Deficiency Resource

2007

AbstractWe describe a second-generation deficiency kit for Drosophila melanogaster composed of molecularly mapped deletions on an isogenic background, covering ∼77% of the Release 5.1 genome. Using a previously reported collection of FRT-bearing P-element insertions, we have generated 655 new deletions and verified a set of 209 deletion-bearing fly stocks. In addition to deletions, we demonstrate how the P elements may also be used to generate a set of custom inversions and duplications, particularly useful for balancing difficult regions of the genome carrying haplo-insufficient loci. We describe a simple computational resource that facilitates selection of appropriate elements for generat…

Chromosome AberrationsGeneticsGenomebiologyMolecular Sequence DataInvestigationsbiology.organism_classificationComputational resourceGenomeSet (abstract data type)Drosophila melanogasterDNA Transposable ElementsDNA Transposable ElementsGeneticsAnimalsDrosophila melanogasterDrosophilaSelection (genetic algorithm)Sequence DeletionGenetics
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Conserved chromosomal clustering of genes governed by chromatin regulators in Drosophila

2008

Transcriptional analysis of chromatin regulator mutants in Drosophila melanogaster identified clusters of functionally related genes conserved in other insect species.

Model organismsanimal structuresTranscription GeneticEvolutionChromosomal Proteins Non-HistoneDrosòfila melanogasterGenome studiesDevelopmentBiologyNon-histone proteinAnimalsDrosophila ProteinsDrosòfila -- GenèticaTranscription factorGeneGeneticsMicroarray analysis techniquesResearchGene Expression ProfilingMutació (Biologia)fungiNuclear Proteinsbiology.organism_classificationChromatin Assembly and DisassemblyChromatinHistoneDrosophila melanogasterDrosofila melanogasterGene Expression RegulationMultigene Familybiology.proteinDrosophila melanogasterDrosophila ProteinGenètica del desenvolupamentTranscription FactorsGenome Biology
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