0000000000860851
AUTHOR
Blanca Simon
showing 2 related works from this author
Identification and Characterization of Extracellular Vesicles and Its DNA Cargo Secreted During Murine Embryo Development
2020
Extracellular vesicles (EVs) are known to transport DNA, but their implications in embryonic implantation are unknown. The aim of this study was to investigate EVs production and secretion by preimplantation embryos and assess their DNA cargo. Murine oocytes and embryos were obtained from six- to eight-week-old females, cultured until E4.5 and analyzed using transmission electron microscopy to examine EVs production. EVs were isolated from E4.5-day conditioned media and quantified by nanoparticle tracking analysis, characterized by immunogold, and their DNA cargo sequenced. Multivesicular bodies were observed in murine oocytes and preimplantation embryos together with the secretion of EVs t…
Exercise-Induced Sustained Ventricular Tachycardia without Structural Heart Disease: A Case Report
2020
Patient: Female, 51-year-old Final Diagnosis: Ventricular tachycardia Symptoms: Chest pain • shortness of breath Medication: — Clinical Procedure: Treadmill stress echocardiogram Specialty: Cardiology Objective: Unusual clinical course Background: Exercise-induced ventricular tachycardia (VT) has been widely reported in patients with preexisting structural heart disease or underlying ischemia and is attributed to reentry tachycardia and abnormal automaticity. However, studies regarding exercise-induced VT in individuals without evident structural heart disease are still limited. Case Report: A 51-year-old woman came to our practice for a treadmill stress echocardiogram. The patient experien…