0000000000867322

AUTHOR

Dagmar Eissner

showing 3 related works from this author

False-positive I-131 whole-body imaging after I-131 therapy for a follicular carcinoma.

1997

A 57-year-old man was treated with ablative radioiodine therapy for follicular thyroid carcinoma. The post-therapeutic whole body scans detected radionuclide accumulation in the area of the right occiput at the site of a cranial defect. The defect was caused by trauma in 1964. Bone scintigraphy did not show increased uptake in this area. Magnetic resonance imaging showed porencephaly, but it did not show a metasasis.

MaleWhole body imagingScintigraphyWhole-Body CountingThyroid carcinomaIodine RadioisotopesAdenocarcinoma FollicularmedicineHumansRadiology Nuclear Medicine and imagingFalse Positive ReactionsThyroid NeoplasmsRadionuclide ImagingBrain Diseasesmedicine.diagnostic_testbusiness.industryThyroidMagnetic resonance imagingOcciputGeneral MedicineMiddle Agedmedicine.diseasePorencephalyMagnetic Resonance Imagingmedicine.anatomical_structureBone scintigraphyOccipital BoneRadiopharmaceuticalsbusinessNuclear medicineClinical nuclear medicine
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Detection of a Dissecting Aortic Aneurysm by Renal Transplant Imaging

1997

After 2 years with a normal post-transplant course a 45-year-old man showed an elevated creatinine level (4.5 mg/dL). Transplantation had been neccessary because of progressive glomerulonephritis. Renal transplant imaging was obtained with 150 Mbq Tc-99m MAG3. The perfusion images showed radionuclide accumulation in the area of the upper abdominal aorta and delayed perfusion of the right iliac artery. Accumulation of Tc-99m MAG3 in the transplant was slow and no filling of the bladder could be observed. Immediately after imaging, the patient developed acute hemorrhagic shock. At emergency surgery, a long dissecting and ruptured aneurysm of the abdominal aorta was seen causing delayed and re…

Malemedicine.medical_specialtyAortic RuptureDissection (medical)Iliac ArteryTechnetium Tc 99m MertiatideAneurysmmedicine.arterymedicineHumansRadiology Nuclear Medicine and imagingRadionuclide ImagingAortic ruptureKidney transplantationAortabusiness.industryAbdominal aortaGeneral MedicineMiddle Agedmedicine.diseaseKidney TransplantationSurgeryTransplantationAortic DissectionRadiologybusinessPerfusionAortic Aneurysm AbdominalCLINICAL NUCLEAR MEDICINE
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Occupancy of striatal D 2 -like dopamine receptors after treatment with the sigma ligand EMD 57445, a putative atypical antipsychotic

1999

Rationale: EMD 57445 (panamesine) is a high affinity sigma ligand with the profile of an atypical antipsychotic in animal studies. It has been reported recently to have antipsychotic activity in schizophrenia. However, its metabolite, EMD 59983, binds also to D2 and D3 dopamine (DA) receptors. Objectives: The aim of this study was to test, using single photon emission computed tomography (SPECT) and [123I]iodobenzamide (IBZM) as the radiotracer, whether EMD 59983 would pass the blood-brain barrier and to what extent it would contribute to the effects of EMD 57445 in schizophrenia. Methods: Two IBZM SPECT-scans were performed in five neuroleptic-free schizophrenic patients (DSM IV), one befo…

AdultMalemedicine.medical_specialtyPyrrolidinesmedicine.drug_classmedicine.medical_treatmentSigma receptorAtypical antipsychoticPanamesinePharmacologychemistry.chemical_compoundIodobenzamidePiperidinesDopamine receptor D3DopamineInternal medicinemedicineHumansReceptors sigmaAntipsychoticOxazolesTomography Emission-Computed Single-PhotonPharmacologyReceptors Dopamine D2Middle AgedCorpus StriatumPyrimidinesEndocrinologychemistryBlood-Brain BarrierDopamine receptorBenzamidesSchizophreniaFemaleAntipsychotic Agentsmedicine.drugPsychopharmacology
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