0000000000867629

AUTHOR

Alexander L. N. Nuijs

0000-0002-9377-6160

showing 3 related works from this author

Spatial differences and temporal changes in illicit drug use in Europe quantified by wastewater analysis

2014

Aims To perform wastewater analyses to assess spatial differences and temporal changes of illicit drug use in a large European population. Design Analyses of raw wastewater over a 1-week period in 2012 and 2013. Setting and Participants Catchment areas of wastewater treatment plants (WWTPs) across Europe, as follows: 2012: 25 WWTPs in 11 countries (23 cities, total population 11.50 million); 2013: 47 WWTPs in 21 countries (42 cities, total population 24.74 million). Measurements Excretion products of five illicit drugs (cocaine, amphetamine, ecstasy, methamphetamine, cannabis) were quantified in wastewater samples using methods based on liquid chromatography coupled to mass spectrom…

cannabisTime FactorsEcstasyEcstasyMethamphetaminesMedicine (miscellaneous)SewageWaste Disposal FluidMass SpectrometryMethamphetamineCocaineMedicineWater treatmentDrug useAmphetamine; cannabis; cocaine; drugs of abuse; ecstasy; methamphetamine; sewagebiologySewageAmphetamine ; Cannabis ; Cocaine ; Drugs of abuse ; Ecstasy ; Methamphetamine ; Sewage6. Clean waterEuropeSubstance Abuse DetectionSubstance abusePsychiatry and Mental healthWastewaterPopulation SurveillanceDrug Abuse And AlcoholismEnvironmental Monitoringdrugs of abuseDrugs of abusemedicine.medical_specialtySubstance-Related DisordersN-Methyl-34-methylenedioxyamphetaminecocaineEnvironmental healthHumanssewageIllicit drugPsychiatryecstasyCannabisCannabinoidsIllicit Drugsbusiness.industryAmphetaminesResearch ReportsEuropean populationmedicine.diseasebiology.organism_classificationMetropolitan areaAmphetamineHuman medicineCannabisbusinessWater Pollutants ChemicalChromatography Liquid
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Spatio‐temporal assessment of illicit drug use at large scale : evidence from 7 years of international wastewater monitoring

2019

Background and aims Wastewater‐based epidemiology is an additional indicator of drug use that is gaining reliability to complement the current established panel of indicators. The aims of this study were to: (i) assess spatial and temporal trends of population‐normalized mass loads of benzoylecgonine, amphetamine, methamphetamine and 3,4‐methylenedioxymethamphetamine (MDMA) in raw wastewater over 7 years (2011–17); (ii) address overall drug use by estimating the average number of combined doses consumed per day in each city; and (iii) compare these with existing prevalence and seizure data. Design Analysis of daily raw wastewater composite samples collected over 1 week per year from 2011 to…

Research ReportWastewater‐based epidemiologyEcstasy/MDMAEpidemiologymedicine.medical_treatmentEcstasyPopulationIllicit drugs030508 substance abuseMedicine (miscellaneous)Wastewater-based epidemiology580 Plants (Botany)Methamphetamine03 medical and health scienceschemistry.chemical_compound0302 clinical medicineCocaineEnvironmental healthAmphetamine ; cocaine ; ecstasy ; MDMA ; illicit drugs ; methamphetamine ; wastewater-based epidemiologyIllicit drugMedicine030212 general & internal medicineeducationAmphetaminewastewater‐based epidemiologyeducation.field_of_studybusiness.industryPharmacology. TherapyMDMAResearch ReportsMethamphetamine6. Clean water3. Good healthStimulantPsychiatry and Mental healthInterdisciplinary Natural SciencesAmphetaminechemistryWastewaterMedicine (miscellaneous); Psychiatry and Mental healthEnvironmental ScienceBenzoylecgonine0305 other medical sciencebusinessmedicine.drugAddiction
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Comparing illicit drug use in 19 European cities through sewage analysis

2012

Abstract: The analysis of sewage for urinary biomarkers of illicit drugs is a promising and complementary approach for estimating the use of these substances in the general population. For the first time, this approach was simultaneously applied in 19 European cities, making it possible to directly compare illicit drug loads in Europe over a 1-week period. An inter-laboratory comparison study was performed to evaluate the analytical performance of the participating laboratories. Raw 24-hour composite sewage samples were collected from 19 European cities during a single week in March 2011 and analyzed for the urinary biomarkers of cocaine, amphetamine, ecstasy, methamphetamine and cannabis u…

Time FactorsEcstasysewage biomarker analysis ; cocaine ; methamphetamine ; amphetamine ; MDMA ; CannabisSewageWaste Disposal FluidMethamphetamineCocaineTandem Mass SpectrometryAigües residualsPer capitaWaste Management and Disposaleducation.field_of_studybiologySewageSewage biomarker analysisMDMAPollutionEuropeChemistryGeographyPopulation Surveillancemedicine.drugEnvironmental MonitoringEnvironmental EngineeringMDMASubstance-Related DisordersPopulationEnvironmental healthmedicineEnvironmental ChemistryIllicit drugHumansCitieseducationBiologyCannabisbusiness.industryCannabinoidsIllicit DrugsAmphetaminesEnvironmental engineeringbiology.organism_classificationAmphetamineCannabisDroguesbusinessBiomarkersWater Pollutants ChemicalWaste disposalChromatography LiquidThe science of the total environment
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