0000000000871651

AUTHOR

D. Friedrich

showing 2 related works from this author

Analysis of the TK enzyme complex induced by HSV types 1 and 2 by means of isoelectric focusing and polyacrylamide gel electrophoresis.

1982

Recently we have described that the Herpes simplex virus (HSV)-induced thymidine kinase (TK) induces AMP- and ADP-dThd-5'-phosphotransferase activities. We now demonstrate the heterogeneity of the described activities in isoelectric focusing experiments and polyacrylamide gel electrophoresis. A TK--mutant of HSV type 1 fails to induce these activities. The activities of the type 1 enzyme complex was neutralized by an anti-HSV-serum. The TK-enzyme complex expressed in LTK--cells transformed to a TK+-phenotype by sheared HSV-1 DNA was compared with the wild type TK complex in isoelectric focusing experiments. Additionally we demonstrate that the HSV type 1 enzyme complex has thymidylate kinas…

Enzyme complexvirusesThymidylate kinase activityBiologymedicine.disease_causeThymidine KinaseFeedbackchemistry.chemical_compoundViral ProteinsVirologymedicineSimplexvirusThymine NucleotidesPolyacrylamide gel electrophoresisIsoelectric focusingWild typeGeneral MedicineVirologyMolecular biologyHerpes simplex virusBiochemistrychemistryThymidine kinaseElectrophoresis Polyacrylamide GelIsoelectric FocusingDNAArchives of virology
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A first search for coincident gravitational waves and high energy neutrinos using LIGO, Virgo and ANTARES data from 2007

2013

A search for high-energy neutrinos coming from the direction of the Sun has been performed using the data recorded by the ANTARES neutrino telescope during 2007 and 2008. The neutrino selection criteria have been chosen to maximize the selection of possible signals produced by the self-annihilation of weakly interacting massive particles accumulated in the centre of the Sun with respect to the atmospheric background. After data unblinding, the number of neutrinos observed towards the Sun was found to be compatible with background expectations. The 90% CL upper limits in terms of spin-dependent and spin-independent WIMP-proton cross-sections are derived and compared to predictions of two sup…

AstrofísicaEXPLOSIONSHigh energyPhotonPOINT SOURCESSUPERCONDUCTING COSMIC STRINGSGravitational waves / experimentsGravitational waves/experimentsAstrophysics01 natural scienceshigh energy neutrinosgravitational wavesgravitational waves / experiment010303 astronomy & astrophysicsQCmedia_commonLine (formation)QBPhysicsHigh Energy Astrophysical Phenomena (astro-ph.HE)GAMMA-RAY BURSTSdark matter detectorsGravitational waves / experiments; Neutrino astronomy; Astronomy and Astrophysicshigh energy neutrinos[SDU.ASTR.HE]Sciences of the Universe [physics]/Astrophysics [astro-ph]/High Energy Astrophysical Phenomena [astro-ph.HE]Settore FIS/01 - Fisica SperimentaleAstrophysics::Instrumentation and Methods for Astrophysicsgravitational waves; gravitational waves / experiments; neutrino astronomy; high energy neutrinos; high energy neutrinosgravitational wavesgravitational wavesparticle physics - cosmology connectionNeutrino astronomyCOSMIC STRINGSRELATIVISTIC JETSNeutrinoAstrophysics - High Energy Astrophysical Phenomenasupersymmetry and cosmology[PHYS.ASTR.HE]Physics [physics]/Astrophysics [astro-ph]/High Energy Astrophysical Phenomena [astro-ph.HE]gravitational waves / experiments; neutrino astronomyTELESCOPEmedia_common.quotation_subjectAstrophysics::High Energy Astrophysical PhenomenaSCIENCE RUNFOS: Physical sciencesddc:500.2GAMMA-RAY BURSTS; CORE-COLLAPSE SUPERNOVAE; SUPERCONDUCTING COSMIC STRINGS; MAGNETAR GIANT FLARES; SCIENCE RUN; RELATIVISTIC JETS; POINT SOURCES; BLACK-HOLES; LOCAL-RATE; TELESCOPEGravitational wavesGeneral Relativity and Quantum CosmologyCORE-COLLAPSE SUPERNOVAESettore FIS/05 - Astronomia e AstrofisicaCoincidentneutrino experiments0103 physical sciences010306 general physicsMAGNETAR GIANT FLARESBLACK-HOLESHigh Energy Astrophysical PhenomenaGravitational waveAstronomy[ PHYS.ASTR.HE ] Physics [physics]/Astrophysics [astro-ph]/High Energy Astrophysical Phenomena [astro-ph.HE]Astronomy and AstrophysicsDRIVENUniverseLIGOGIANT FLARESLOCAL-RATEFISICA APLICADALUMINOSITYRADIATIONHigh Energy Physics::Experiment[ SDU.ASTR.HE ] Sciences of the Universe [physics]/Astrophysics [astro-ph]/High Energy Astrophysical Phenomena [astro-ph.HE]Experiments[PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]
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