Analysis of the histopathological artifacts in punch biopsies of the normal oral mucosa

2008

Objectives: To study the most frequent artifacts of punch biopsies of the healthy oral mucosa, distinguishing between those attributable to the surgical technique and those resulting from sample processing in the laboratory. Study design: A total of 186 samples of oral mucosa (dorsal lingual mucosa) were obtained from 186 adult albino rats by the experienced oral surgeons, evaluating the presence of artifacts attributable to the surgical technique (crush, splits, fragmentation, pseudocysts and haemorrhage) and those attributable to sample processing in the laboratory (orientation). Results: The distribution of artifacts attributable to the surgical procedure was as follows: crush 16.67%, sp…