0000000000876417
AUTHOR
Sankarasekaran Shanmugaraju
Fluorescent 3-amino-1,8-naphthalimide Tröger’s bases (3-amino-TBNaps) incorporating protected α-amino acids
Abstract The synthesis of 3-amino-1,8-naphthalimide Troger’s base’s (TBNaps) 2–4, possessing several amino acids at the imide terminus, from the corresponding 3-amino-1,8-naphthalimide (Naps) units is described. The solid-state X-ray crystal structure of the related 3-amino-TBNaps piperidino-ethyl derivative 1, and its supramolecular packing is also outlined. In these molecules (as demonstrated from the X-ray structure of 1), the two Naps units have an orthogonal arrangement that makes them potentially attractive β-turn mimics for incorporation into peptide and polypeptide structures. The ground and the excited state properties of these systems were evaluated in a range of solvents that var…
CCDC 2092211: Experimental Crystal Structure Determination
Related Article: Samantha A. Murphy, Caroline Phelan, Sankarasekaran Shanmugaraju, Salvador Blasco, Thorfinnur Gunnlaugsson|2021|Tetrahedron Lett.|83|153405|doi:10.1016/j.tetlet.2021.153405