Electrophysiological Effects of Direct Electrical Stimulations During Awake Brain Surgery: Methodological Considerations
International audience; IRECT electrical stimulation (DES) has long been used to perform real-time functional mapping of the brain. More recently, this technique was introduced in the neurosurgery of slow-growing and infiltrative brain tumors to guide the resection with great success. By generating transient perturbations, this method allows the real-time identification of both cortical areas and subcortical networks that are essential for the function. Thus, as much as possible, non-functional tissue can be removed while minimizing the sequelae. However, the understanding of the electrophysiological effects of DES and, in particular its remote propagation, remains an open and key question.…
Case report: Remote neuromodulation with direct electrical stimulation of the brain, as evidenced by intra-operative EEG recordings during wide-awake neurosurgery
Letter to the editor; International audience
"Awake Surgery" of Slow-Growing Tumors and Cortical Excitability Measured by EEG Recordings. Preliminary Results
International audience; To investigate interhemispheric imbalance following "awake surgeries" of slow-growing tumors we recorded EEG in a visuo-manual RT paradigm. Increase of cortical excitability within the ipsilesional hemisphere was signed by increased ERPs amplitude for two patients. The cortical excitability in the lesioned hemisphere may be increased to maintain performances and cerebral plasticity.