Author: Agata Marek

0000000000877972

AUTHOR

Agata Marek

Experimental and theoretical characterization of chelidonic acid structure

Abstract Chelidonic acid (4-oxo-4H-pyran-2,6-dicarboxylic acid) is present in plants of Papaveraceae family, especially in Chelidonium majus. Due to its anticancer, antibacterial, hepatoprotective, and antioxidant properties, it has been used in medical treatments. In this work, the X-ray structure of methanol solvate of chelidonic acid was determined. Layers of chelidonic acid are held by hydrogen bonds via COOH and C = O fragments and additionally bridged by methanol. The formed H-bond network between two acid units is different from typical –COOH dimers observed, e.g., in crystals of isophtalic acid. The molecular structure of 2,6-dimethyl-γ-pyrone (2Me4PN) and chelidonic acid, a 2,6-dic…

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CCDC 2144108: Experimental Crystal Structure Determination

Related Article: Natalina Makieieva, Teobald Kupka, Grzegorz Spaleniak, Oimahmad Rahmonov, Agata Marek, Alfred Błażytko, Leszek Stobiński, Nataliya Stadnytska, Danuta Pentak, Aneta Buczek, Małgorzata A. Broda, Piotr Kuś, Joachim Kusz, Maria Książek|2022|Struct.Chem.|33|2133|doi:10.1007/s11224-022-02026-7

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