0000000000877975
AUTHOR
Nataliya Stadnytska
Experimental and theoretical characterization of chelidonic acid structure
Abstract Chelidonic acid (4-oxo-4H-pyran-2,6-dicarboxylic acid) is present in plants of Papaveraceae family, especially in Chelidonium majus. Due to its anticancer, antibacterial, hepatoprotective, and antioxidant properties, it has been used in medical treatments. In this work, the X-ray structure of methanol solvate of chelidonic acid was determined. Layers of chelidonic acid are held by hydrogen bonds via COOH and C = O fragments and additionally bridged by methanol. The formed H-bond network between two acid units is different from typical –COOH dimers observed, e.g., in crystals of isophtalic acid. The molecular structure of 2,6-dimethyl-γ-pyrone (2Me4PN) and chelidonic acid, a 2,6-dic…
Effect of extraction solvent on total phenolic content, total flavonoid content and antioxidant activity of Cetraria islandica
Oxidative stress may lead to a number of diseases such as atherosclerosis, nephrotoxicity, liver cirrhosis, cancers, diabetes, and Alzheimer disease. Medicinal plants are an important source of antioxidants. Therefore, the antioxidant potential of Cetraria islandica was evaluated in this work. The coarse powder of leaf of Cetraria islandica was extracted in Soxhlet apparatus, with ethanol (90%) and ethanolic extract of Cetraria islandica (EECI) was further processed for phytochemical screening, total phenol content, total flavonoid content, and various in vitro antioxidant assays. The phytochemicals present in EECI were glycosides, carbohydrates, triterpenoids, proteins and amino acids, gum…
CCDC 2144108: Experimental Crystal Structure Determination
Related Article: Natalina Makieieva, Teobald Kupka, Grzegorz Spaleniak, Oimahmad Rahmonov, Agata Marek, Alfred Błażytko, Leszek Stobiński, Nataliya Stadnytska, Danuta Pentak, Aneta Buczek, Małgorzata A. Broda, Piotr Kuś, Joachim Kusz, Maria Książek|2022|Struct.Chem.|33|2133|doi:10.1007/s11224-022-02026-7