0000000000880853

AUTHOR

Mabel Brunotto

showing 3 related works from this author

Oral cancer associated with chronic mechanical irritation of the oral mucosa

2017

Background Most of the studies dealing with Chronic Mechanical Irritation (CMI) and Oral Cancer (OC) only considered prosthetic and dental variables separately, and CMI functional factors are not registered. Thus, the aim of this study was to assess OC risk in individuals with dental, prosthetic and functional CMI. Also, we examined CMI presence in relation to tumor size. Material and Methods A case-control study was carried out from 2009 to 2013. Study group were squamous cell carcinoma cases; control group was patients seeking dental treatment in the same institution. Results 153 patients were studied (Study group n=53, Control group n=100). CMI reproducibility displayed a correlation coe…

AdultMalemedicine.medical_specialtyMultivariate analysischemical and pharmacologic phenomenacomplex mixturesMechanical irritation03 medical and health sciences0302 clinical medicineRisk FactorsInternal medicineStatistical significanceparasitic diseasesmedicineHumansOral mucosaRisk factorGeneral DentistryStomatitisOral Medicine and PathologyTumor sizebusiness.industryResearchCase-control studyCancer030206 dentistryMiddle Aged:CIENCIAS MÉDICAS [UNESCO]medicine.diseasebacterial infections and mycosesBiomechanical Phenomenamedicine.anatomical_structureOtorhinolaryngology030220 oncology & carcinogenesisCase-Control StudiesUNESCO::CIENCIAS MÉDICASSurgeryFemaleMouth Neoplasmsbusinesstherapeutics
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Malignancy Risk Models for Oral Lesions

2013

Objectives: The aim of this work was to assess risk habits, clinical and cellular phenotypes and TP53 DNA changes in oral mucosa samples from patients with Oral Potentially Malignant Disorders (OPMD), in order to create models that enable genotypic and phenotypic patterns to be obtained that determine the risk of lesions becoming malignant. Study Design: Clinical phenotypes, family history of cancer and risk habits were collected in clinical histories. TP53 gene mutation and morphometric-morphological features were studied, and multivariate models were applied. Three groups were estabished: a) oral cancer (OC) group (n=10), b) OPMD group (n=10), and c) control group (n=8). Results: An avera…

OncologyMalePathologyGenotypeTP53Family historyYoung adultMouth neoplasmCiencias Médicas y de la SaludAged 80 and overpublic health//purl.org/becyt/ford/3.1 [https]Middle Aged:CIENCIAS MÉDICAS [UNESCO]Ciencias de la saludMedicina BásicaUNESCO::CIENCIAS MÉDICASOPMD//purl.org/becyt/ford/3 [https]FemaleMouth NeoplasmsRisk assessmentAdultmedicine.medical_specialtyGenética HumanaContext (language use)OdontologíaMalignancyRisk AssessmentYoung AdultInternal medicinemedicineHumansGeneral DentistryAgedOral Medicine and PathologyModels Statisticalbusiness.industryCancermedicine.diseaseGenes p53Cross-Sectional StudiesOtorhinolaryngologyORAL CANCERTP53; ORAL POTENTIALLY MALIGNANT DISORDERS; RISK FACTORS; GENOTYPE; PHENOTYPEMutationSurgeryResearch-ArticlebusinessMouth DiseasesMedicina Oral, Patología Oral y Cirugía Bucal
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Evaluation of clinical dental variables to build classifiers to predict celiac disease

2008

Objective: The aim of this study was to evaluate the use of salivary variables to build statistical models for predicting celiac disease in symptomatic children. Materials and Methods: the study group consisted of 52 children with celiac disease diagnosed by bowel biopsy, grade III or IV (4 to 12 years old, both sexes) and 23 healthy children as a control group. A logistic regression model was applied to evaluate an individual’s belonging to one group or another. The performance of the model was evaluated by the value of area under the ROC curve. The salivary variables included in the model were the concentration of total proteins, calcium, Ca / P molar ratio, buffer capacity and salivary f…

Evaluation Studies as TopicDiagnosisDental ResearchUNESCO::CIENCIAS MÉDICASCeliac disease:CIENCIAS MÉDICAS [UNESCO]
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