0000000000882144

AUTHOR

Mikko Melarto

showing 2 related works from this author

Dihydrooxazine Oxides as Key Intermediates in Organocatalytic Michael Additions of Aldehydes to Nitroalkenes

2012

Pause and play: dihydrooxazine oxides are stable intermediates that are protonated directly, without the intermediacy of the zwitterions, in organocatalytic Michael additions of aldehydes and nitroalkenes (see scheme, R=alkyl). Protonation of these species explains both the role of the acid co-catalyst in these reactions, and the observed stereochemistry when the reaction is conducted with α-alkylnitroalkenes.

chemistry.chemical_classificationchemistryOrganic chemistryProtonationGeneral ChemistryNuclear magnetic resonance spectroscopyGeneral Medicineta116CatalysisAlkylAngewandte Chemie
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ChemInform Abstract: Dihydrooxazine Oxides as Key Intermediates in Organocatalytic Michael Additions of Aldehydes to Nitroalkenes.

2013

Pause and play: dihydrooxazine oxides are stable intermediates that are protonated directly, without the intermediacy of the zwitterions, in organocatalytic Michael additions of aldehydes and nitroalkenes (see scheme, R=alkyl). Protonation of these species explains both the role of the acid co-catalyst in these reactions, and the observed stereochemistry when the reaction is conducted with α-alkylnitroalkenes.

chemistry.chemical_classificationAddition reactionChemistryOrganocatalysisProtonationGeneral MedicineMedicinal chemistryAlkylChemInform
researchProduct