0000000000882167

AUTHOR

Carmen Peña

showing 2 related works from this author

Microbiological effects of an antiseptic mouthrinse in irradiated cancer patients

2010

Objective: To assess the microbiological effects of an antiseptic, non-alcohol based mouth-rinse containing chlorhexidine and cetylpyridinium chloride, in patients undergoing radiation therapy for head-and-neck cancer. Study Design: This was a parallel, double-blind, prospective, randomized clinical trial, including patients irradiated as part of the therapy of head-and-neck cancer, aged 18-75, with at least 10 teeth, and willing to sign an informed consent. Cancer patients were randomly assigned to one of the two treatments (test mouth-rinse or a placebo). Three visits were scheduled (baseline, 14 and 28 days). Microbiological findings were evaluated in tongue, mucosa and subgingival sampl…

AdultMaleAdolescentmedicine.drug_classmedicine.medical_treatmentMouthwashesDentistryCetylpyridiniumPlacebolaw.inventionYoung AdultAntisepticRandomized controlled trialDouble-Blind MethodlawTongueMedicineHumansProspective StudiesProspective cohort studyGeneral DentistryAgedMouthbusiness.industryChlorhexidineChlorhexidineCancerMiddle Agedmedicine.disease:CIENCIAS MÉDICAS [UNESCO]Radiation therapymedicine.anatomical_structureOtorhinolaryngologyHead and Neck NeoplasmsUNESCO::CIENCIAS MÉDICASAnti-Infective Agents LocalSurgeryFemalebusinessmedicine.drug
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Mucositis in irradiated cancer patients: effects of an antiseptic mouthrinse.

2009

Objective: To assess the effects of an antiseptic, non-alcohol based mouth-rinse containing chlorhexidine and cetylpyridinium chloride, in preventing the oral complications associated to radiation therapy in head-and-neck cancer patients. Study design: This was a parallel, double blind, prospective, randomized clinical trial. Cancer patients were randomly assigned to one of the two treatments (test mouth-rinse or a placebo). Three visits were scheduled (baseline, 14 and 28 days). Different outcome variables were evaluated: mucositis, plaque and gingival indices, stimulated saliva and salivary pH. Results: 70 patients were screened and 36 were included. The presence and the degree of mucosit…

Malemedicine.medical_specialtySalivamedicine.drug_classMouthwashesDentistryCetylpyridiniumPlaceboCetylpyridinium chloridelaw.inventionchemistry.chemical_compoundAntisepticRandomized controlled trialDouble-Blind MethodlawInternal medicinemedicineMucositisHumansProspective StudiesRadiation InjuriesGeneral DentistryStomatitisbusiness.industryChlorhexidineChlorhexidineCancerMiddle Aged:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseOtorhinolaryngologychemistryHead and Neck NeoplasmsUNESCO::CIENCIAS MÉDICASAnti-Infective Agents LocalSurgeryFemalebusinessmedicine.drugMedicina oral, patologia oral y cirugia bucal
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