0000000000886828

AUTHOR

Camilla Alovisi

Supplementary_material – Supplemental material for Treat and extend versus fixed regimen in neovascular age related macular degeneration: A systematic review and meta-analysis

Supplemental material, Supplementary_material for Treat and extend versus fixed regimen in neovascular age related macular degeneration: A systematic review and meta-analysis by Matteo Fallico, Andrew J Lotery, Antonio Longo, Teresio Avitabile, Vincenza Bonfiglio, Andrea Russo, Nicolò Castellino, Guglielmo Parisi, Alfredo Pulvirenti, Chiara Eandi, Gilda Cennamo, Claudio Furino, Maria Vittoria Cicinelli, Camilla Alovisi and Michele Reibaldi in European Journal of Ophthalmology

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Treat and extend versus fixed regimen in neovascular age related macular degeneration: A systematic review and meta-analysis

Purpose: To compare efficacy of treat and extend (T&E) versus fixed regimen treatment protocols in neovascular age-related macular degeneration (nAMD). Methods: Randomized clinical trials (RCTs) comparing T&E versus fixed regimen protocols for nAMD were systematically searched. Primary outcome was to compare the mean best corrected visual acuity (BCVA) change in T&E regimen versus fixed regimen. Secondary outcomes were change in the mean optical coherence tomography (OCT) central retinal thickness (CRT) and mean number of injections. Standardized mean difference (SMD) along with 95% confidence intervals (CIs) were calculated. Random-effect models were used for meta-analyses. Res…

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