0000000000893555

AUTHOR

Martin Pretl

showing 4 related works from this author

Long-term positive airway pressure therapy is associated with reduced total cholesterol levels in patients with obstructive sleep apnea : data from t…

2020

Background and aim: Obstructive sleep apnea (OSA) is an independent risk factor for dyslipidemia. The current study examined the effects of positive airway pressure (PAP) treatment on lipid status in the European Sleep Apnea Database (ESADA). Methods: The prospective cohort study enrolled 1564 OSA subjects (74% male, mean age 54 ± 11y, body mass index (BMI) 32.7 ± 6.6 kg/m2 and apnea-hypopnea index (AHI) 40.3 ± 24.4 n/h) undergoing PAP therapy for at least three months (mean 377.6 ± 419.5 days). Baseline and follow-up total cholesterol (TC) from nine centers were analyzed. Repeated measures and logistic regression tests (adjusted for age, sex, weight changes, lipid lowering medication, PAP …

cardiovascular riskAdultMalemedicine.medical_specialtySettore MED/10 - Malattie Dell'Apparato RespiratorioPositive airway pressure03 medical and health sciences0302 clinical medicineInternal medicinePositive airway pressuremedicineCardiovascular risk Cholesterol Hypoxia Sleep apneaHumanspositive airway pressureProspective StudiesRisk factorProspective cohort studyHypoxiaAgedSleep Apnea ObstructiveFramingham Risk ScoreContinuous Positive Airway Pressurebusiness.industryhypoxiaSleep apneaSleep apneacholesterolGeneral MedicineMiddle Agedmedicine.diseasesleep apneaCardiovascular riskObstructive sleep apneaCardiovascular risk ; Cholesterol ; Hypoxia ; Positive airway pressure ; Sleep apnea.Cholesterol030228 respiratory systemPatient ComplianceFemaleHuman medicinebusinessBody mass index030217 neurology & neurosurgeryDyslipidemiaSleep medicine
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Obstructive sleep apnoea in adult patients post-tonsillectomy

2021

Background: The impact of removing the upper airway lymphoid tissue and in particular, tonsillectomy, in adults with OSA has not been demonstrated in large populations. Aims: To compare the severity of OSA and the prevalence of cardiovascular, metabolic and respiratory co-morbidities between patients with OSA who had undergone previous tonsillectomy and those who had not. Methods: The 19,711 participants in this study came from the European sleep apnea database (ESADA) which comprises data from unselected adult patients aged 18–80 years with a history of symptoms suggestive of OSA referred to sleep centers throughout Europe. Results: There were no differences between the two groups in terms…

AdultPediatricsmedicine.medical_specialtymedicine.medical_treatment[SDV]Life Sciences [q-bio]ESADALymphoid tissue overgrowthSettore MED/10 - Malattie Dell'Apparato Respiratorio03 medical and health sciencesSleep apnoea0302 clinical medicinemedicineHumansMass indexRespiratory systemTonsillectomySleep Apnea ObstructiveAdult patientsbusiness.industrySleep apneaGeneral MedicineESADA ; Lymphoid tissue overgrowth ; Sleep apnoea ; Tonsillectomy.medicine.diseaseSleep in non-human animalsrespiratory tract diseasesTonsillectomy[SDV] Life Sciences [q-bio]Europe030228 respiratory systemDiabetes Mellitus Type 2Lower prevalenceTonsillectomy.AirwaybusinessSleep030217 neurology & neurosurgery
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Fixed But Not Autoadjusting Positive Airway Pressure Attenuates the Time-dependent Decline in Glomerular Filtration Rate in Patients With OSA

2018

Abstract: BACKGROUND: The impact of treating OSA on renal function decline is controversial. Previous studies usually included small samples and did not consider specific effects of different CPAP modalities. The aim of this study was to evaluate the respective influence of fixed and autoadjusting CPAP modes on estimated glomerular filtration rate (eGFR) in a large sample of patients derived from the prospective European Sleep Apnea Database cohort. METHODS: In patients of the European Sleep Apnea Database, eGFR prior to and after follow-up was calculated by using the Chronic Kidney Disease-Epidemiology Collaboration equation. Three study groups were investigated: untreated patients (n = 14…

Pulmonary and Respiratory Medicinemedicine.medical_specialtyUrologyRenal functionSettore MED/10 - Malattie Dell'Apparato RespiratorioEgfr declineCritical Care and Intensive Care MedicineOSA03 medical and health sciences0302 clinical medicinePositive airway pressuremedicineautomatic CPAPIn patientKidneyglomerular filtration ratetherapybusiness.industrySleep apneafixed CPAPta3121medicine.diseaserespiratory tract diseasesLarge samplemedicine.anatomical_structure030228 respiratory systemCohortHuman medicinebusinessCardiology and Cardiovascular Medicine030217 neurology & neurosurgery
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Regional differences in characteristics of patients referred to European sleep centers. Results from the European Sleep Apnea Database (ESADA)

2012

SLEEP APNEASettore MED/10 - Malattie Dell'Apparato Respiratorio
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