0000000000901499

AUTHOR

Bastienne Brauksiepe

showing 2 related works from this author

Differential expression pattern of the novel serine/threonine kinase, STK33, in mice and men

2005

Serine/threonine kinase 33 (STK33/Stk33) is a recently discovered gene whose inferred amino acid sequence translation displays characters typical for a calcium/calmodulin dependent kinase (CAMK). In this study we analysed the STK33/Stk33 RNA and protein distribution and the localization of the protein. The STK33/Stk33 expression pattern resembles those of some related members of the CAMK group. STK33/Stk33 displays a nonubiquitous and, in most tissues, low level of expression. It is highly expressed in testis, particularly in cells from the spermatogenic epithelia. Moreover, significant expression is detected in lung epithelia, alveolar macrophages, horizontal cells in the retina and in emb…

Serine/threonine-specific protein kinaseGSK-3Ca2+/calmodulin-dependent protein kinaseAKT1Cell Biologyc-RafBiologyMolecular BiologyBiochemistryMolecular biologyCAMKAKT3MAP2K7FEBS Journal
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Serine/threonine-kinase 33 (Stk33) – Component of the neuroendocrine network?

2016

The present study was conducted to investigate the expression of serine/threonine-kinase 33 (Stk33) in neuronal structures of the central nervous system in rat and hamster as well as the presence of the protein in the brain of higher mammals, using a polyclonal antibody on cryosections of fixed brains. We found a distinct immunostaining pattern that included intense fluorescence of the ependymal lining of cerebral ventricles, and of hypothalamic tanycytes and their processes. We further observed intense staining of magnocellular neurons in the hypothalamic paraventricular, supraoptic and accessory neurosecretory nuclei, in particular the circular nuclei, and less intense stained neurons in …

Male0301 basic medicineEpendymal CellBlotting WesternCentral nervous systemProtein Serine-Threonine KinasesBiologyRats Sprague-Dawley03 medical and health sciences0302 clinical medicineCricetinaemedicineAnimalsHumansMolecular BiologyAgedNeuronsSerine/threonine-specific protein kinaseMice Inbred BALB CGeneral NeuroscienceTupaiidaeBrainColocalizationHuman brainImmunohistochemistryNeurosecretory SystemsCell biology030104 developmental biologymedicine.anatomical_structurenervous systemHypothalamusMagnocellular cellFemaleNeurology (clinical)Neuroscience030217 neurology & neurosurgeryImmunostainingPapioDevelopmental BiologyBrain Research
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