0000000000903422

AUTHOR

Johannes Weidenhammer

showing 2 related works from this author

Exercise training improves peak oxygen consumption and haemodynamics in patients with severe pulmonary arterial hypertension and inoperable chronic t…

2015

Aims The impact of exercise training on the right heart and pulmonary circulation has not yet been invasively assessed in patients with pulmonary hypertension (PH) and right heart failure. This prospective randomized controlled study investigates the effects of exercise training on peak VO2/kg, haemodynamics, and further clinically relevant parameters in PH patients. Methods and results Eighty-seven patients with pulmonary arterial hypertension and inoperable chronic thrombo-embolic PH (54% female, 56 ± 15 years, 84% World Health Organization functional class III/IV, 53% combination therapy) on stable disease-targeted medication were randomly assigned to a control and training group. Medica…

Malemedicine.medical_specialtyCardiac outputHypertension PulmonaryVentricular Dysfunction RightCardiac indexHemodynamics610 Medicine & health030204 cardiovascular system & hematology2705 Cardiology and Cardiovascular Medicine03 medical and health sciences0302 clinical medicineOxygen ConsumptionHeart RateInternal medicineThromboembolismHeart rateNatriuretic Peptide BrainmedicineHumansProspective StudiesPulmonary Wedge PressureCardiac OutputPulmonary wedge pressureProspective cohort studyAnalysis of VarianceExercise Tolerancebusiness.industryMiddle Agedmedicine.diseasePulmonary hypertensionPeptide FragmentsSurgeryExercise Therapymedicine.anatomical_structureTreatment Outcome030228 respiratory systemChronic DiseaseVascular resistanceCardiologyExercise TestFemaleVascular Resistance10178 Clinic for PneumologyCardiology and Cardiovascular MedicinebusinessBiomarkersEuropean heart journal
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Exercise training improves peak oxygen consumption and hemodynamics in patients with pulmonary hypertension – A prospective, randomized, controlled t…

2016

Aims: This prospective randomized controlled study investigates the effects of exercise training on peak VO 2 /kg, hemodynamics and further clinically relevant parameters in pulmonary hypertension (PH) patients. Methods: Eighty-seven patients with pulmonary arterial hypertension and inoperable chronic thromboembolic PH (54% female, 56±15years, 84% WHO functional class III/IV, 53% combination therapy) on stable disease-targeted medication were randomly assigned to a control and training group. Medication remained unchanged during the study period. Non-invasive assessments and right heart catheterization at rest and during exercise were performed at baseline and after 15 weeks. Primary endpoi…

Right heart catheterizationmedicine.medical_specialtyVentricular functionCombination therapybusiness.industryHemodynamicsmedicine.diseasePulmonary hypertensionlaw.invention03 medical and health sciences0302 clinical medicine030228 respiratory systemRandomized controlled triallawInternal medicineClinical endpointPhysical therapyCardiologyMedicineIn patient030212 general & internal medicinebusiness1.2 Rehabilitation and Chronic Care
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